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Name | Galanin receptor type 3 |
---|---|
Species | Homo sapiens (Human) |
Gene | GALR3 |
Synonym | GAL3-R Galnr3 GALR-3 GALR3 GAL3 receptor |
Disease | Cognitive disorders |
Length | 368 |
Amino acid sequence | MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE |
UniProt | O60755 |
Protein Data Bank | N/A |
GPCR-HGmod model | O60755 |
3D structure model | This predicted structure model is from GPCR-EXP O60755. |
BioLiP | N/A |
Therapeutic Target Database | T98494 |
ChEMBL | CHEMBL2731 |
IUPHAR | 245 |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
106 | MLS000716936 | C16H14F3N3O5S | 417.359 | 12 / 2 | 3.1 | No |
415 | Dibromosalicil | C14H8Br2O4 | 400.022 | 4 / 2 | 4.7 | Yes |
5352 | MLS000833548 | C18H17F5N4S | 416.414 | 8 / 1 | 4.0 | Yes |
5954 | MLS000730667 | C19H26ClN3O2 | 363.886 | 4 / 1 | 3.6 | Yes |
6260 | MLS000040609 | C17H20N4O | 296.374 | 4 / 1 | 3.5 | Yes |
7062 | SMR000033717 | C8H16INO2 | 285.125 | 3 / 0 | N/A | N/A |
7363 | MLS001209947 | C17H12ClN3O4S | 389.81 | 6 / 1 | 4.5 | Yes |
8822 | BDBM97075 | C28H25Cl2N3O3 | 522.426 | 5 / 0 | 4.8 | No |
9987 | MolPort-000-723-526 | C17H31BrN2 | 343.353 | 2 / 1 | N/A | N/A |
14458 | MLS000566658 | C20H21BrN4O2S | 461.378 | 6 / 0 | 3.0 | Yes |
14500 | CHEMBL378877 | C14H8Cl2N2O | 291.131 | 2 / 1 | 3.8 | Yes |
21492 | MLS003271268 | C22H27N7O4 | 453.503 | 9 / 3 | 0.3 | Yes |
22951 | SMR000220470 | C18H20N4 | 292.386 | 3 / 2 | 4.1 | Yes |
28407 | CHEMBL209480 | C15H9F3N2O | 290.245 | 5 / 1 | 3.4 | Yes |
29037 | MLS000538535 | C15H15BrN2O2 | 335.201 | 3 / 1 | 3.1 | Yes |
30772 | MLS001125299 | C21H25N5O | 363.465 | 3 / 1 | 2.8 | Yes |
31592 | MLS000054201 | C15H13N3O4 | 299.286 | 6 / 1 | 1.6 | Yes |
33982 | MLS002920666 | C12H7ClN4O6 | 338.66 | 7 / 1 | 4.1 | Yes |
35827 | MolPort-000-720-960 | C17H27BrN2 | 339.321 | 2 / 1 | N/A | N/A |
38174 | CHEMBL506553 | C139H210N42O43 | 3157.46 | 48 / 48 | -15.9 | No |
39853 | MLS002701634 | C20H12O3 | 300.313 | 3 / 1 | 3.6 | Yes |
41874 | MLS000040640 | C18H25N5O2 | 343.431 | 6 / 1 | 4.2 | Yes |
42613 | MLS000519909 | C26H30N4O5 | 478.549 | 6 / 1 | 3.0 | Yes |
43898 | MLS000712366 | C16H14BrN3 | 328.213 | 2 / 1 | 3.8 | Yes |
44948 | SMR000001597 | C19H16N4O3S | 380.422 | 7 / 0 | 3.1 | Yes |
46945 | MLS002253020 | C20H18N2O3 | 334.375 | 4 / 1 | 3.6 | Yes |
47560 | CHEMBL209737 | C14H9ClN2O | 256.689 | 2 / 1 | 3.3 | Yes |
48892 | MLS001000456 | C17H19N3O2S | 329.418 | 6 / 1 | 4.2 | Yes |
51013 | MLS002636314 | C23H17F2N3O4S2 | 501.523 | 9 / 2 | 5.0 | No |
52651 | MLS001002564 | C17H14N2O4 | 310.309 | 5 / 1 | 2.3 | Yes |
54795 | MLS001177315 | C25H26N2O4 | 418.493 | 4 / 1 | 3.8 | Yes |
55934 | MLS002164468 | C20H28N6OS | 400.545 | 6 / 0 | 2.8 | Yes |
56610 | MLS000094981 | C9H6N6O4 | 262.185 | 8 / 1 | 0.9 | Yes |
58524 | MLS000704511 | C10H6N2OS | 202.231 | 3 / 1 | 1.4 | Yes |
559107 | SMR000147834 | C20H18N6O3S | 422.463 | 9 / 4 | 1.0 | Yes |
60392 | MLS001180182 | C14H15BrN4S2 | 383.326 | 6 / 2 | N/A | N/A |
60847 | SMR000010338 | C15H14ClN3 | 271.748 | 3 / 2 | N/A | N/A |
559180 | MLS000766664 | C14H11BrN4O5 | 395.169 | 7 / 2 | 1.9 | Yes |
559187 | SMR000147833 | C18H14N6OS | 362.411 | 7 / 4 | 1.1 | Yes |
63444 | MLS001029145 | C29H38ClN7O | 536.121 | 6 / 1 | 4.3 | No |
63830 | MLS000082037 | C24H23N3O4 | 417.465 | 5 / 0 | 4.0 | Yes |
64028 | MLS001030649 | C25H28ClN3O2S | 470.028 | 5 / 1 | 4.9 | Yes |
64847 | NSC720623 | C25H26F3N3O3S | 505.556 | 7 / 0 | N/A | No |
67485 | MLS001174949 | C18H22N2O3 | 314.385 | 4 / 1 | 3.4 | Yes |
68273 | Dihydrorotenone | C23H24O6 | 396.439 | 6 / 0 | 4.2 | Yes |
68274 | Dihydrorotenone | C23H24O6 | 396.439 | 6 / 0 | 4.2 | Yes |
70542 | Pyridaben | C19H25ClN2OS | 364.932 | 3 / 0 | 5.2 | No |
73261 | MLS000675919 | C12H8F4N2O2S | 320.262 | 8 / 0 | 2.5 | Yes |
74560 | MLS000664008 | C26H28N2O2S | 432.582 | 4 / 1 | 4.6 | Yes |
74702 | MLS000571626 | C13H16N4O3 | 276.296 | 5 / 1 | 1.4 | Yes |
74905 | 2,6-Di-tert-butyl-4-nitrophenol | C14H21NO3 | 251.326 | 3 / 1 | 4.7 | Yes |
76533 | SMR000006308 | C17H26N4O4S | 382.479 | 7 / 3 | 2.8 | Yes |
78688 | Galanin-1-16 | C78H116N20O21 | 1669.91 | 23 / 22 | -2.9 | No |
79213 | AC1M530P | C23H23N2OS+ | 375.51 | 3 / 0 | 5.9 | No |
81875 | SMR000122163 | C21H35BrN2 | 395.429 | 2 / 2 | N/A | N/A |
82740 | MLS001179913 | C20H16N2O3 | 332.359 | 4 / 1 | 3.1 | Yes |
87709 | MLS000732847 | C23H25N3O2 | 375.472 | 4 / 1 | 3.9 | Yes |
88578 | N-Benzylquinazolin-4-amine | C15H13N3 | 235.29 | 3 / 1 | 3.9 | Yes |
89210 | Exciton | C21H23ClN2O4S | 434.935 | 6 / 0 | N/A | N/A |
91049 | MLS000085820 | C15H15N5S | 297.38 | 6 / 1 | 3.7 | Yes |
93188 | MLS000684433 | C18H19NO | 265.356 | 2 / 2 | 3.0 | Yes |
96859 | Skf-81297 | C16H16ClNO2 | 289.759 | 3 / 3 | 2.7 | Yes |
96954 | MLS000683121 | C17H14N2O5S | 358.368 | 7 / 1 | 2.1 | Yes |
96994 | MLS000662478 | C17H16N4OS | 324.402 | 5 / 1 | 3.0 | Yes |
97214 | Salmeterol | C25H37NO4 | 415.574 | 5 / 4 | 3.9 | Yes |
97382 | MLS001215955 | C24H30O5 | 398.499 | 5 / 2 | 2.4 | Yes |
99173 | MLS003119183 | C19H18N2O4S | 370.423 | 6 / 2 | 2.7 | Yes |
99910 | MLS001100829 | C25H26FN3O3 | 435.499 | 6 / 1 | 4.0 | Yes |
100845 | SMR000221403 | C18H13N5OS2 | 379.456 | 7 / 1 | 3.0 | Yes |
101585 | MLS000998903 | C21H30FN3OS | 391.549 | 6 / 1 | 3.9 | Yes |
101827 | 2-ethyl-N-(5-nitropyridin-2-yl)butanamide | C11H15N3O3 | 237.259 | 4 / 1 | 1.9 | Yes |
104108 | BDBM70384 | C23H21N5O2 | 399.454 | 5 / 2 | 3.2 | Yes |
104132 | MLS001180182 | C14H14N4S2 | 302.414 | 6 / 1 | 4.0 | Yes |
106315 | CHEMBL1323872 | C23H23IN2OS | 502.414 | 4 / 0 | N/A | No |
106462 | CHEMBL1588926 | C25H25BrN2 | 433.393 | 2 / 0 | N/A | N/A |
107720 | MLS-0380219.0001 | C18H17F2N5O | 357.365 | 5 / 1 | 2.3 | Yes |
560937 | SMR000060129 | C19H20N2O5 | 356.378 | 6 / 3 | 3.8 | Yes |
118389 | MLS000547376 | C13H12Cl3N3O2 | 348.608 | 3 / 1 | 3.9 | Yes |
123281 | MLS002249163 | C15H16N4O5S2 | 396.436 | 8 / 1 | 1.4 | Yes |
123504 | Galanin rat | C92H135N27O26 | 2035.26 | 29 / 28 | -6.9 | No |
125723 | MLS003115736 | C11H13NOS | 207.291 | 2 / 1 | 1.7 | Yes |
553920 | SNAP-398299 | C27H24F3N3O2 | 479.503 | 7 / 0 | 5.7 | No |
127210 | MLS000701132 | C13H13Cl2N3O | 298.167 | 2 / 1 | 3.0 | Yes |
127993 | MLS001007488 | C16H17N3O2S | 315.391 | 6 / 1 | 3.3 | Yes |
130599 | AKOS015896602 | C17H22ClNO3 | 323.817 | 5 / 5 | N/A | N/A |
131806 | BAS 00918756 | C7H11ClN4O2S | 250.701 | 6 / 3 | 0.8 | Yes |
134279 | MLS000391427 | C21H18Cl2N2O3S | 449.346 | 5 / 1 | 5.4 | No |
138246 | ritodrine | C17H21NO3 | 287.359 | 4 / 4 | 2.3 | Yes |
138991 | MLS001160878 | C20H23N3O5 | 385.42 | 6 / 1 | 2.7 | Yes |
138992 | AKOS033707998 | C20H23N3O5 | 385.42 | 6 / 1 | 2.7 | Yes |
139967 | MLS000717757 | C19H30N2 | 286.463 | 2 / 1 | 5.1 | No |
141336 | CID 73950903 | C21H21IN2S2 | 492.437 | 4 / 0 | N/A | N/A |
144261 | Bio3H4 | C13H7F3N6 | 304.236 | 8 / 1 | 3.6 | Yes |
144651 | MLS003107056 | C24H45NO8 | 475.623 | 9 / 8 | N/A | No |
145355 | MLS000833557 | C21H22ClN5OS | 427.951 | 5 / 1 | 4.9 | Yes |
148164 | GNF-Pf-2344 | C17H30N2 | 262.441 | 2 / 1 | 6.0 | No |
149138 | MLS003231005 | C19H14BrClN2O | 401.688 | 2 / 0 | 6.2 | No |
149359 | MLS000077260 | C16H16N4OS2 | 344.451 | 6 / 1 | 3.9 | Yes |
149652 | MLS003120629 | C23H20N2O4 | 388.423 | 5 / 1 | 3.6 | Yes |
150640 | MLS003230991 | C23H15F3N2O | 392.381 | 5 / 0 | 6.6 | No |
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