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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000683121
Molecular formula	C17H14N2O5S
IUPAC name	ethyl 2-[2-[(4-oxochromene-2-carbonyl)amino]-1,3-thiazol-4-yl]acetate
Molecular weight	358.368
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.1
Synonyms	2-[2-[[oxo-(4-oxo-1-benzopyran-2-yl)methyl]amino]-4-thiazolyl]acetic acid ethyl ester CHEMBL1371941 SMR000322946 AB00137835-03 ethyl 2-[2-[(4-oxidanylidenechromen-2-yl)carbonylamino]-1,3-thiazol-4-yl]ethanoate SR-01000443341-3 BDBM97107 HMS2684F04 361478-78-6 cid_3548924 MolPort-003-015-800 SR-01000443341 AC1MTDNS ethyl 2-[2-[(4-oxochromene-2-carbonyl)amino]-1,3-thiazol-4-yl]acetate ZINC3892568 2-[2-[(4-ketochromene-2-carbonyl)amino]thiazol-4-yl]acetic acid ethyl ester MCULE-1526238396 ethyl 2-(2-(4-oxo-4H-chromene-2-carboxamido)thiazol-4-yl)acetate Oprea1_597861 SR-01000443341-1 AKOS017104111 F0463-0247 [ Show all ]
Inchi Key	GHZHRMPDHBKSMK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H14N2O5S/c1-2-23-15(21)7-10-9-25-17(18-10)19-16(22)14-8-12(20)11-5-3-4-6-13(11)24-14/h3-6,8-9H,2,7H2,1H3,(H,18,19,22)
PubChem CID	3548924
ChEMBL	CHEMBL1371941
IUPHAR	N/A
BindingDB	97107
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
96954	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368

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