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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14


MM-align is an algorithm for structurally aligning a pair of multiple-chain complexes of protein and/or nucleic acid molecules (RNA/DNA). The multiple chains in each complex are first joined, in every possible order, and then simultaneously aligned with cross-chain alignments prevented. An optimal alignment between two complexes, as well as the overall TM-score, will be reported.

Update history: MM-align has been updated to MM-align++, with major updates including

  • Alignment of hybrid complexes consisting of both protein and nucleic acids, such as ribosomes, is now supported.
  • A new assignment algorithm is implemented for fast chain-level correspondence search to improve the accuracy of large homo-oligomers alignment.
  • Support for the PDBx/mmCIF format is newly included in MM-align++, in addition to the legacy PDB format used in MM-align.
  • Fixed issue in the old MM-align program where alignments were not generated a pair of complex structures have divergent structures.
  • The new MM-align++ program includes five different chain-level initial alignment methods to ensure accurate initial alignment generation, in contrast to the old MM-align program that only implements one chain-level initial alignment (gapless threading).

MM-align on-line [View example output]



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MM-align other information


References

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