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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000085820
Molecular formula	C15H15N5S
IUPAC name	2-amino-6-(cyanomethylsulfanyl)-4-cyclohexylpyridine-3,5-dicarbonitrile
Molecular weight	297.38
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.7
Synonyms	cid_3237836 SR-01000529311-3 2-azanyl-6-(cyanomethylsulfanyl)-4-cyclohexyl-pyridine-3,5-dicarbonitrile AC1MMF99 MCULE-6303549904 2-amino-6-(cyanomethylsulfanyl)-4-cyclohexylpyridine-3,5-dicarbonitrile SR-01000529311 2-amino-6-[(cyanomethyl)sulfanyl]-4-cyclohexylpyridine-3,5-dicarbonitrile EU-0052420 STK661503 AKOS005524271 2-amino-6-(cyanomethylthio)-4-cyclohexyl-dinicotinonitrile CHEMBL1523520 SR-01000529311-1 2-amino-6-[(cyanomethyl)thio]-4-cyclohexylpyridine-3,5-dicarbonitrile HMS2280A21 ZINC19831054 A2241/0094343 BDBM83738 SMR000020949 2-amino-6-(cyanomethylthio)-4-cyclohexylpyridine-3,5-dicarbonitrile [ Show all ]
Inchi Key	FZLVVKJYXRJMRX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H15N5S/c16-6-7-21-15-12(9-18)13(10-4-2-1-3-5-10)11(8-17)14(19)20-15/h10H,1-5,7H2,(H2,19,20)
PubChem CID	3237836
ChEMBL	CHEMBL1523520
IUPHAR	N/A
BindingDB	83738
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
91049	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
91048	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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