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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000675919
Molecular formula	C12H8F4N2O2S
IUPAC name	4-(4-fluorophenyl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine
Molecular weight	320.262
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	2.5
Synonyms	4-(4-fluorophenyl)-2-(methylsulfonyl)-6-(trifluoromethyl)pyrimidine SCHEMBL19805665 EU-0089240 STK340647 BDBM43524 4-(4-fluorophenyl)-2-mesyl-6-(trifluoromethyl)pyrimidine CHEMBL1375338 SMR000297077 AC1MGK68 HMS2589H09 ZINC215166 CCG-27092 MolPort-002-099-979 4-(4-fluorophenyl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine cid_2987363 ST50636099 AKOS003395219 MCULE-6117419219 [ Show all ]
Inchi Key	FABYEEIARBZBHO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H8F4N2O2S/c1-21(19,20)11-17-9(6-10(18-11)12(14,15)16)7-2-4-8(13)5-3-7/h2-6H,1H3
PubChem CID	2987363
ChEMBL	CHEMBL1375338
IUPHAR	N/A
BindingDB	43524
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
73261	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
73259	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
73260	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
471959	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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