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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Galanin receptor type 3
Species	Homo sapiens (Human)
Gene	GALR3
Synonym	GAL3-R Galnr3 GALR-3 GALR3 GAL3 receptor
Disease	Cognitive disorders
Length	368
Amino acid sequence	MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
UniProt	O60755
Protein Data Bank	N/A
GPCR-HGmod model	O60755
3D structure model	This predicted structure model is from GPCR-EXP O60755.
BioLiP	N/A
Therapeutic Target Database	T98494
ChEMBL	CHEMBL2731
IUPHAR	245
DrugBank	N/A

Ligand

Name	MLS002920666
Molecular formula	C12H7ClN4O6
IUPAC name	N-(4-chlorophenyl)-2,4,6-trinitroaniline
Molecular weight	338.66
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.1
Synonyms	34749-63-8 BDBM91446 N-(4-Chlorophenyl)-2,4,6-trinitroaniline # SCHEMBL2681112 CHEMBL1889401 AC1Q1X4P N-(4-chlorophenyl)-2,4,6-trinitro-aniline 4'-Chloro-2,4,6-trinitrodiphenylamine BVQWERYAWIDLFA-UHFFFAOYSA-N NSC-157487 SMR001798253 A822488 cid_291920 (4-chlorophenyl)-picryl-amine AC1Q3RDQ N-(4-Chlorophenyl)-2,4,6-trinitroaniline 4-chlorophenyl (2,4,6-trinitrophenyl)amine NSC157487 ZINC72137932 AC1L6GVY [ Show all ]
Inchi Key	BVQWERYAWIDLFA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H7ClN4O6/c13-7-1-3-8(4-2-7)14-12-10(16(20)21)5-9(15(18)19)6-11(12)17(22)23/h1-6,14H
PubChem CID	291920
ChEMBL	CHEMBL1889401
IUPHAR	N/A
BindingDB	91446
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<1110.0 nM	, PubChem BioAssay data set	BindingDB,ChEMBL

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