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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000732847
Molecular formula	C23H25N3O2
IUPAC name	3-ethyl-4-[[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]methyl]piperazin-2-one
Molecular weight	375.472
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.9
Synonyms	3-ethyl-4-[[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]methyl]piperazin-2-one CHEMBL1603032 4-[(2-biphenyl-4-yl-5-methyl-1,3-oxazol-4-yl)methyl]-3-ethylpiperazin-2-one MCULE-4739893114 BDBM46409 3-ethyl-4-[[5-methyl-2-(4-phenylphenyl)-4-oxazolyl]methyl]-2-piperazinone cid_16190638 4-{[2-(4-biphenylyl)-5-methyl-1,3-oxazol-4-yl]methyl}-3-ethyl-2-piperazinone 3-ethyl-4-[[5-methyl-2-(4-phenylphenyl)oxazol-4-yl]methyl]piperazin-2-one HMS2755M13 SMR000316479 [ Show all ]
Inchi Key	FUSSCZQVVQIIPW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25N3O2/c1-3-21-22(27)24-13-14-26(21)15-20-16(2)28-23(25-20)19-11-9-18(10-12-19)17-7-5-4-6-8-17/h4-12,21H,3,13-15H2,1-2H3,(H,24,27)
PubChem CID	16190638
ChEMBL	CHEMBL1603032
IUPHAR	N/A
BindingDB	46409
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
87709	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
87708	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
87710	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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