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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000998903
Molecular formula	C21H30FN3OS
IUPAC name	2-[1-(2,2-dimethylpropyl)-4-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]methyl]piperazin-2-yl]ethanol
Molecular weight	391.549
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.9
Synonyms	2-(1-(2,2-dimethylpropyl)-4-{[4-(4-fluorophenyl)-1,3-thiazol-2-yl]methyl}piperazin-2-yl)ethanol cid_23723905 SR-01000171970-3 2-[4-[[4-(4-fluorophenyl)thiazol-2-yl]methyl]-1-neopentyl-piperazin-2-yl]ethanol SR-01000171970 2-[1-(2,2-dimethylpropyl)-4-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]methyl]piperazin-2-yl]ethanol HMS2842M18 MolPort-005-078-580 2-(1-(2,2-dimethylpropyl)-4-{[4-(4-fluorophenyl)-1,3-thiazol-2-yl]methyl}-2-piperazinyl)ethanol CHEMBL1720771 SR-01000171970-1 2-[1-(2,2-dimethylpropyl)-4-[[4-(4-fluorophenyl)-2-thiazolyl]methyl]-2-piperazinyl]ethanol MCULE-9026269767 BDBM97134 SMR000495716 [ Show all ]
Inchi Key	GOUYUKOYEGKQEP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H30FN3OS/c1-21(2,3)15-25-10-9-24(12-18(25)8-11-26)13-20-23-19(14-27-20)16-4-6-17(22)7-5-16/h4-7,14,18,26H,8-13,15H2,1-3H3
PubChem CID	23723905
ChEMBL	CHEMBL1720771
IUPHAR	N/A
BindingDB	97134
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
101585	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
101586	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
475461	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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