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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000716936
Molecular formula	C16H14F3N3O5S
IUPAC name	2-[3-(2,4-dimethoxyphenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid
Molecular weight	417.359
Hydrogen bond acceptor	12
Hydrogen bond donor	2
XlogP	3.1
Synonyms	HMS2650I03 ASN 13121597 MolPort-000-124-602 2-[3-(2,4-dimethoxyphenyl)-5-hydroxy-5-(trifluoromethyl)-2-pyrazolin-1-yl]thiazole-4-carboxylic acid 2-[3-(2,4-dimethoxyphenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-4-thiazolecarboxylic acid CHEMBL1543980 STL447485 AC1N4MFE MCULE-8682610489 BDBM97103 REGID_for_CID_4157793 2-[3-(2,4-dimethoxyphenyl)-5-hydroxy-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid 2-[3-(2,4-dimethoxyphenyl)-5-oxidanyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid cid_4157793 AKOS005224685 2-[3-(2,4-dimethoxyphenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid SMR000278453 [ Show all ]
Inchi Key	AADHNFIRCRYOGZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H14F3N3O5S/c1-26-8-3-4-9(12(5-8)27-2)10-6-15(25,16(17,18)19)22(21-10)14-20-11(7-28-14)13(23)24/h3-5,7,25H,6H2,1-2H3,(H,23,24)
PubChem CID	4157793
ChEMBL	CHEMBL1543980
IUPHAR	N/A
BindingDB	97103
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
106	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
462983	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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