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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Galanin receptor type 3
Species	Homo sapiens (Human)
Gene	GALR3
Synonym	GAL3-R Galnr3 GALR-3 GALR3 GAL3 receptor
Disease	Cognitive disorders
Length	368
Amino acid sequence	MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
UniProt	O60755
Protein Data Bank	N/A
GPCR-HGmod model	O60755
3D structure model	This predicted structure model is from GPCR-EXP O60755.
BioLiP	N/A
Therapeutic Target Database	T98494
ChEMBL	CHEMBL2731
IUPHAR	245
DrugBank	N/A

Ligand

Name	SMR000033717
Molecular formula	C8H16INO2
IUPAC name	[(2Z)-2-(1,3-dioxolan-4-ylidene)ethyl]-trimethylazanium;iodide
Molecular weight	285.125
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	None
Synonyms	[(2Z)-2-(1,3-dioxolan-4-ylidene)ethyl]-trimethylazanium iodide AC1NY9EM HMS2274E08 SR-01000406368 MLS000047708 SR-01000406368-1 CHEMBL1375102 [ Show all ]
Inchi Key	AJNCXPSSFAXWAG-ZYFYRQFPSA-M
Inchi ID	InChI=1S/C8H16NO2.HI/c1-9(2,3)5-4-8-6-10-7-11-8;/h4H,5-7H2,1-3H3;1H/q+1;/p-1/b8-4-;
PubChem CID	5771435
ChEMBL	CHEMBL1375102
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<29905.0 nM	PubChem BioAssay data set	ChEMBL

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