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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS002164468
Molecular formula	C20H28N6OS
IUPAC name	2-(1-cyclopropyltetrazol-5-yl)sulfanyl-1-[4-[(4-propan-2-ylphenyl)methyl]piperazin-1-yl]ethanone
Molecular weight	400.545
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.8
Synonyms	2-[(1-cyclopropyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]-1-(4-{[4-(propan-2-yl)phenyl]methyl}piperazin-1-yl)ethan-1-one Z151960050 879354-91-3 HMS3076F04 2-(1-cyclopropyltetrazol-5-yl)sulfanyl-1-[4-[(4-propan-2-ylphenyl)methyl]piperazin-1-yl]ethanone AKOS033394573 MolPort-005-516-404 2-[(1-cyclopropyl-5-tetrazolyl)thio]-1-[4-[(4-propan-2-ylphenyl)methyl]-1-piperazinyl]ethanone CHEMBL1357535 ZINC23731397 MCULE-5669073000 2-[(1-cyclopropyl-1,2,3,4-tetrazol-5-yl)sulfanyl]-1-[4-[(4-propan-2-ylphenyl)methyl]piperazin-1-yl]ethanone BDBM97163 SMR001246841 2-[(1-cyclopropyltetrazol-5-yl)thio]-1-[4-(4-isopropylbenzyl)piperazino]ethanone cid_9261962 AC1PNMQE [ Show all ]
Inchi Key	DBQUNKYLWWHSNA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H28N6OS/c1-15(2)17-5-3-16(4-6-17)13-24-9-11-25(12-10-24)19(27)14-28-20-21-22-23-26(20)18-7-8-18/h3-6,15,18H,7-14H2,1-2H3
PubChem CID	9261962
ChEMBL	CHEMBL1357535
IUPHAR	N/A
BindingDB	97163
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
55934	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
55933	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
469836	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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