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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000221403
Molecular formula	C18H13N5OS2
IUPAC name	2-[(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)sulfanyl]-N-quinolin-4-ylacetamide
Molecular weight	379.456
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.0
Synonyms	ZINC2338946 2-[(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)sulfanyl]-N-quinolin-4-yl-ethanamide AC1LZLVN MCULE-4148143000 SCHEMBL17456944 2-[[5-(3-pyridyl)-1,3,4-thiadiazol-2-yl]thio]-N-(4-quinolyl)acetamide BDBM97082 SR-01000304189-1 cid_1952659 2-[(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)sulfanyl]-N-quinolin-4-ylacetamide AKOS000585483 MLS000331927 2-{[5-(pyridin-3-yl)-1,3,4-thiadiazol-2-yl]sulfanyl}-N-(quinolin-4-yl)acetamide STK781768 2-(5-Pyridin-3-yl-[1,3,4]thiadiazol-2-ylsulfanyl)-N-quinolin-4-yl-acetamide A3844/0163236 HMS2584C07 2-[[5-(3-pyridinyl)-1,3,4-thiadiazol-2-yl]thio]-N-(4-quinolinyl)acetamide BAS 11409550 MolPort-002-020-196 SR-01000304189 728014-95-7 CHEMBL1482468 [ Show all ]
Inchi Key	GNSPUMPBYJIQBG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H13N5OS2/c24-16(21-15-7-9-20-14-6-2-1-5-13(14)15)11-25-18-23-22-17(26-18)12-4-3-8-19-10-12/h1-10H,11H2,(H,20,21,24)
PubChem CID	1952659
ChEMBL	CHEMBL1482468
IUPHAR	N/A
BindingDB	97082
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
100845	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368

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