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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Galanin receptor type 3
Species	Homo sapiens (Human)
Gene	GALR3
Synonym	GAL3-R Galnr3 GALR-3 GALR3 GAL3 receptor
Disease	Cognitive disorders
Length	368
Amino acid sequence	MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
UniProt	O60755
Protein Data Bank	N/A
GPCR-HGmod model	O60755
3D structure model	This predicted structure model is from GPCR-EXP O60755.
BioLiP	N/A
Therapeutic Target Database	T98494
ChEMBL	CHEMBL2731
IUPHAR	245
DrugBank	N/A

Ligand

Name	2-ethyl-N-(5-nitropyridin-2-yl)butanamide
Molecular formula	C11H15N3O3
IUPAC name	2-ethyl-N-(5-nitropyridin-2-yl)butanamide
Molecular weight	237.259
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.9
Synonyms	2-ethyl-N-(5-nitro-2-pyridyl)butyramide Cambridge id 7252184 SMR000272231 cid_2931999 ZINC4460024 2-ethyl-N-(5-nitro(2-pyridyl))butanamide AKOS003277112 MLS000680645 ST50922702 AC1MG8E5 HMS2641D24 2-ethyl-N-(5-nitro-2-pyridinyl)butanamide BDBM97100 MolPort-001-539-823 2-ethyl-N-{5-nitro-2-pyridinyl}butanamide CHEMBL1344311 STK433816 AK-968/12715256 MCULE-7325718981 [ Show all ]
Inchi Key	GPDNDHDFFZPJGP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H15N3O3/c1-3-8(4-2)11(15)13-10-6-5-9(7-12-10)14(16)17/h5-8H,3-4H2,1-2H3,(H,12,13,15)
PubChem CID	2931999
ChEMBL	CHEMBL1344311
IUPHAR	N/A
BindingDB	97100
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<29886.0 nM	, PubChem BioAssay data set	BindingDB,ChEMBL

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