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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Galanin receptor type 3
Species	Homo sapiens (Human)
Gene	GALR3
Synonym	GAL3-R Galnr3 GALR-3 GALR3 GAL3 receptor
Disease	Cognitive disorders
Length	368
Amino acid sequence	MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
UniProt	O60755
Protein Data Bank	N/A
GPCR-HGmod model	O60755
3D structure model	This predicted structure model is from GPCR-EXP O60755.
BioLiP	N/A
Therapeutic Target Database	T98494
ChEMBL	CHEMBL2731
IUPHAR	245
DrugBank	N/A

Ligand

Name	MLS003231005
Molecular formula	C19H14BrClN2O
IUPAC name	6-bromo-3-[(3-chlorophenyl)methyl]-2-(furan-2-yl)-8-methylimidazo[1,2-a]pyridine
Molecular weight	401.688
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	6.2
Synonyms	BDBM97190 cid_53299527 6-bromanyl-3-[(3-chlorophenyl)methyl]-2-(furan-2-yl)-8-methyl-imidazo[1,2-a]pyridine 6-bromo-3-[(3-chlorophenyl)methyl]-2-(furan-2-yl)-8-methylimidazo[1,2-a]pyridine 6-bromo-3-(3-chlorobenzyl)-2-(2-furyl)-8-methyl-imidazo[1,2-a]pyridine CHEMBL2136078 6-bromo-3-[(3-chlorophenyl)methyl]-2-(2-furanyl)-8-methylimidazo[1,2-a]pyridine SMR001913570 [ Show all ]
Inchi Key	JESMIUAIFXBPCA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H14BrClN2O/c1-12-8-14(20)11-23-16(10-13-4-2-5-15(21)9-13)18(22-19(12)23)17-6-3-7-24-17/h2-9,11H,10H2,1H3
PubChem CID	53299527
ChEMBL	CHEMBL2136078
IUPHAR	N/A
BindingDB	97190
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	8411.0 nM	, PubChem BioAssay data set	BindingDB,ChEMBL

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