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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000662478
Molecular formula	C17H16N4OS
IUPAC name	2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-quinolin-4-ylacetamide
Molecular weight	324.402
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.0
Synonyms	ST45108680 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-quinolin-4-ylacetamide AKOS004104696 HMS2711O24 MolPort-002-095-942 2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-4-quinolinylacetamide CBKinase1_010395 SR-01000288037-1 A3681/0156127 CHEMBL1487720 ZINC00528219 2-(4,6-dimethylpyrimidin-2-ylthio)-N-(4-quinolyl)acetamide BDBM97095 MCULE-2596065254 SMR000295572 2-[(4,6-dimethylpyrimidin-2-yl)thio]-N-(4-quinolyl)acetamide CBKinase1_022795 SR-01000288037-4 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-quinolin-4-yl-ethanamide AC1LINTI cid_934786 ZINC528219 2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-(4-quinolinyl)acetamide BRD-K54100566-001-01-2 SR-01000288037 [ Show all ]
Inchi Key	GIBBLZZAENGNDT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H16N4OS/c1-11-9-12(2)20-17(19-11)23-10-16(22)21-15-7-8-18-14-6-4-3-5-13(14)15/h3-9H,10H2,1-2H3,(H,18,21,22)
PubChem CID	934786
ChEMBL	CHEMBL1487720
IUPHAR	N/A
BindingDB	97095
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
96994	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
474887	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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