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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Galanin receptor type 3
Species	Homo sapiens (Human)
Gene	GALR3
Synonym	GAL3-R Galnr3 GALR-3 GALR3 GAL3 receptor
Disease	Cognitive disorders
Length	368
Amino acid sequence	MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
UniProt	O60755
Protein Data Bank	N/A
GPCR-HGmod model	O60755
3D structure model	This predicted structure model is from GPCR-EXP O60755.
BioLiP	N/A
Therapeutic Target Database	T98494
ChEMBL	CHEMBL2731
IUPHAR	245
DrugBank	N/A

Ligand

Name	MLS000717757
Molecular formula	C19H30N2
IUPAC name	4-heptyl-2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-imine
Molecular weight	286.463
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.1
Synonyms	4-heptyl-2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-imine cid_16192765 AC1LXCS8 SMR000279125 (4-heptyl-2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-ylidene)amine;hydrobromide BDBM97099 4-heptyl-2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-imine;hydrobromide GNF-Pf-2480 AKOS016033849 4-Heptyl-1,2,3,4,5,6,7,8-octahydro-cyclopenta[b]quinolin-9-ylideneamine CHEMBL525680 BAS 00138334 [ Show all ]
Inchi Key	IRHMEKGTYJBSMM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H30N2/c1-2-3-4-5-8-14-21-17-12-7-6-10-15(17)19(20)16-11-9-13-18(16)21/h20H,2-14H2,1H3
PubChem CID	1799112
ChEMBL	N/A
IUPHAR	N/A
BindingDB	97099
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<1108.0 nM	N/A	BindingDB

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