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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS-0380219.0001
Molecular formula	C18H17F2N5O
IUPAC name	N-[1-(2,4-difluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2-methylpyrazole-3-carboxamide
Molecular weight	357.365
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.3
Synonyms	MCULE-2814549250 SR-01000174054 N-[1-(2,4-difluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2-methyl-3-pyrazolecarboxamide CHEMBL1492752 N-[1-[2,4-bis(fluoranyl)phenyl]-4,5,6,7-tetrahydroindazol-4-yl]-2-methyl-pyrazole-3-carboxamide SR-01000174054-1 BDBM62270 N-[1-(2,4-difluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2-methyl-pyrazole-3-carboxamide cid_24793944 SMR000658701 MLS001072510 SR-01000174054-3 N-[1-(2,4-difluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2-methylpyrazole-3-carboxamide [ Show all ]
Inchi Key	GXLKSVCDXUMIAV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H17F2N5O/c1-24-17(7-8-21-24)18(26)23-14-3-2-4-15-12(14)10-22-25(15)16-6-5-11(19)9-13(16)20/h5-10,14H,2-4H2,1H3,(H,23,26)
PubChem CID	24793944
ChEMBL	CHEMBL1492752
IUPHAR	N/A
BindingDB	62270
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
107720	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
476204	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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