You can:
| Name | 5-hydroxytryptamine receptor 1B |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Htr1b |
| Synonym | HTR1D2 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 5-HT1Dbeta 5-HT1DB 5-HT1B serotonin receptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 386 |
| Amino acid sequence | MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG |
| UniProt | P28564 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3459 |
| IUPHAR | 2 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 488 |  CHEMBL54125 | C22H21FN4 | 360.436 | 4 / 0 | 4.7 | Yes |
| 1866 |  CHEMBL53662 | C23H23FN4O | 390.462 | 5 / 0 | 4.7 | Yes |
| 4225 |  CHEMBL25984 | C15H23NO | 233.355 | 2 / 0 | 3.8 | Yes |
| 4976 |  CHEMBL50188 | C25H36N2O4 | 428.573 | 5 / 0 | 4.2 | Yes |
| 5545 |  CHEMBL50722 | C25H36N2O5 | 444.572 | 6 / 0 | 4.3 | Yes |
| 5767 |  paroxetine | C19H20FNO3 | 329.371 | 5 / 1 | 3.5 | Yes |
| 5914 |  CHEMBL50722 | C27H38N2O9 | 534.606 | 10 / 2 | N/A | No |
| 6361 |  CHEMBL163281 | C16H23NO2 | 261.365 | 3 / 0 | 3.2 | Yes |
| 7261 |  CHEMBL54914 | C15H17N5 | 267.336 | 4 / 0 | 2.4 | Yes |
| 7852 |  CHEMBL63114 | C14H15N3S | 257.355 | 3 / 0 | 4.2 | Yes |
| 8095 |  CHEMBL291620 | C18H29NO | 275.436 | 2 / 0 | 4.8 | Yes |
| 8213 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 9616 |  CHEMBL418678 | C20H19FN4S | 366.458 | 5 / 0 | 4.7 | Yes |
| 10269 |  CHEMBL298649 | C22H22FN5 | 375.451 | 5 / 0 | 4.3 | Yes |
| 10287 |  doxorubicin | C27H29NO11 | 543.525 | 12 / 6 | 1.3 | No |
| 11072 |  tryptamine | C10H12N2 | 160.22 | 1 / 2 | 1.6 | Yes |
| 11703 |  Propranolol, L- | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 11704 |  DEXPROPRANOLOL | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 11713 |  AC1OCGE3 | C16H22NO2+ | 260.357 | 2 / 2 | 3.0 | Yes |
| 11717 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 11809 |  CHEMBL54266 | C23H32N2O4S | 432.579 | 6 / 1 | 4.3 | Yes |
| 12304 |  CHEMBL52800 | C22H22FN5O | 391.45 | 6 / 0 | 4.3 | Yes |
| 13550 |  N-Methylserotonin | C11H14N2O | 190.246 | 2 / 3 | 0.7 | Yes |
| 13651 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 14247 |  180083-23-2 | C32H32N4O3 | 520.633 | 6 / 0 | 5.6 | No |
| 15091 |  disulfiram | C10H20N2S4 | 296.524 | 4 / 0 | 3.9 | Yes |
| 521936 |  AM-0902 | C17H15ClN6O2 | 370.797 | 6 / 0 | 2.3 | Yes |
| 16794 |  Pipamperone | C21H30FN3O2 | 375.488 | 5 / 1 | 2.0 | Yes |
| 16879 |  Glemanserin | C20H25NO | 295.426 | 2 / 1 | 3.8 | Yes |
| 17895 |  Bmy-7378 | C22H31N3O3 | 385.508 | 5 / 0 | 2.8 | Yes |
| 18211 |  CHEMBL49932 | C22H21N5O2 | 387.443 | 6 / 0 | 3.7 | Yes |
| 19635 |  CHEMBL287651 | C17H23NO2 | 273.376 | 3 / 2 | 3.5 | Yes |
| 19993 |  CHEMBL53490 | C14H15N5 | 253.309 | 4 / 1 | 1.9 | Yes |
| 21905 |  CHEMBL157447 | C11H10ClIN2 | 332.569 | 2 / 0 | N/A | N/A |
| 21913 |  CHEMBL85602 | C23H28N2OS | 380.55 | 3 / 0 | 4.1 | Yes |
| 522112 |  CHEMBL3775436 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 522192 |  CHEMBL3775769 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 22831 |  CHEMBL163167 | C13H15NO2 | 217.268 | 3 / 1 | 1.6 | Yes |
| 23288 |  CHEMBL303986 | C19H23N5OS | 369.487 | 5 / 0 | 3.2 | Yes |
| 23724 |  CHEMBL2376487 | C14H15N3O2 | 257.293 | 3 / 2 | 2.0 | Yes |
| 23770 |  Arotinolol | C15H21N3O2S3 | 371.532 | 7 / 3 | 2.3 | Yes |
| 25280 |  CHEMBL162170 | C15H21NO2 | 247.338 | 3 / 1 | 2.9 | Yes |
| 25959 |  CHEMBL62612 | C22H24N4S | 376.522 | 4 / 0 | 5.4 | No |
| 26045 |  LISURIDE | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 26504 |  RWJ-25730 | C25H36N4O2 | 424.589 | 4 / 0 | 2.7 | Yes |
| 26593 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26875 |  CHEMBL28178 | C16H15F3N4 | 320.319 | 6 / 1 | 3.5 | Yes |
| 26946 |  terconazole | C26H31Cl2N5O3 | 532.466 | 7 / 0 | 4.8 | No |
| 27168 |  CHEMBL2203713 | C18H22N4S | 326.462 | 4 / 2 | 2.9 | Yes |
| 27797 |  CHEMBL279646 | C25H30FN5O2 | 451.546 | 5 / 2 | 3.1 | Yes |
| 28267 |  CHEMBL62777 | C17H27NO | 261.409 | 2 / 1 | 4.5 | Yes |
| 29765 |  CHEMBL364005 | C14H15ClN2 | 246.738 | 1 / 2 | 2.8 | Yes |
| 31414 |  CHEMBL306384 | C29H31N5O3 | 497.599 | 7 / 1 | 4.9 | Yes |
| 33235 |  CHEMBL410531 | C22H20ClFN4 | 394.878 | 4 / 0 | 5.3 | No |
| 33886 |  Binospirone | C20H26N2O4 | 358.438 | 5 / 1 | 2.3 | Yes |
| 34709 |  CHEMBL274922 | C27H34N6O3 | 490.608 | 5 / 3 | 2.3 | Yes |
| 35638 |  miconazole | C18H14Cl4N2O | 416.123 | 2 / 0 | 5.3 | No |
| 35913 |  CHEMBL1788284 | C11H14N2O | 190.246 | 2 / 3 | 1.6 | Yes |
| 35914 |  CHEMBL1744074 | C11H14N2O | 190.246 | 2 / 3 | 1.6 | Yes |
| 37761 |  CHEMBL335010 | C22H26N2O2 | 350.462 | 4 / 0 | 3.8 | Yes |
| 38625 |  3-[2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one | C20H21F3N4O | 390.41 | 6 / 1 | 3.3 | Yes |
| 40031 |  oxprenolol | C15H23NO3 | 265.353 | 4 / 2 | 2.1 | Yes |
| 40193 |  CHEMBL153136 | C26H38N4O2 | 438.616 | 4 / 0 | 3.2 | Yes |
| 41312 |  CHEMBL60318 | C20H22FN3OS | 371.474 | 5 / 0 | 3.9 | Yes |
| 42410 |  CHEMBL62911 | C21H23N4S+ | 363.503 | 3 / 0 | 4.6 | Yes |
| 42926 |  3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | C13H14N2 | 198.269 | 1 / 2 | 1.8 | Yes |
| 43158 |  64022-27-1 | C8H11ClN4 | 198.654 | 4 / 1 | 0.5 | Yes |
| 44087 |  CHEMBL50456 | C21H19Cl2N5 | 412.318 | 4 / 0 | 5.1 | No |
| 44537 |  CHEMBL276031 | C19H26N2O | 298.43 | 2 / 1 | 3.9 | Yes |
| 44811 |  Bacitracin A | C66H103N17O16S | 1422.71 | 21 / 17 | -4.1 | No |
| 45834 |  CHEMBL1744073 | C12H16N2O | 204.273 | 2 / 2 | 2.2 | Yes |
| 45835 |  CHEMBL1788282 | C12H16N2O | 204.273 | 2 / 2 | 2.2 | Yes |
| 47861 |  CHEMBL11787 | C26H32N2O4 | 436.552 | 5 / 1 | 4.2 | Yes |
| 47976 |  CHEMBL162282 | C15H21NO2 | 247.338 | 3 / 1 | 2.9 | Yes |
| 48452 |  CHEMBL1210154 | C19H16N2O2S | 336.409 | 4 / 1 | 4.7 | Yes |
| 48462 |  SCHEMBL4318956 | C19H16N2O2S | 336.409 | 4 / 1 | 4.7 | Yes |
| 522981 |  CHEMBL3799529 | C22H25F3N4O2S | 466.523 | 8 / 1 | 4.6 | Yes |
| 51345 |  CHEMBL133375 | C28H40N2O4 | 468.638 | 5 / 0 | 4.9 | Yes |
| 52215 |  N,N-Di-n-propylserotonin | C16H24N2O | 260.381 | 2 / 2 | 3.0 | Yes |
| 52586 |  CHEMBL2376491 | C20H20N2 | 288.394 | 1 / 2 | 3.8 | Yes |
| 52779 |  CHEMBL165290 | C13H17NO2 | 219.284 | 3 / 1 | 2.0 | Yes |
| 53764 |  CHEMBL2376482 | C14H15BrN2 | 291.192 | 1 / 2 | 2.9 | Yes |
| 53954 |  CHEMBL65736 | C17H20N4S | 312.435 | 4 / 0 | 3.9 | Yes |
| 54613 |  CHEMBL48925 | C25H34N2O4 | 426.557 | 5 / 1 | 4.6 | Yes |
| 57382 |  CHEMBL14010 | C24H28N2O4S | 440.558 | 5 / 0 | 3.5 | Yes |
| 57403 |  CHEMBL298534 | C24H31FN2O3 | 414.521 | 5 / 1 | 4.7 | Yes |
| 57911 |  CHEMBL53195 | C32H35N7 | 517.681 | 6 / 0 | 5.6 | No |
| 59000 |  CHEMBL66307 | C26H23ClN4S | 459.008 | 4 / 0 | 7.0 | No |
| 59143 |  CHEMBL131011 | C22H26N2O2 | 350.462 | 4 / 0 | 3.7 | Yes |
| 59264 |  CHEMBL64167 | C20H23N3OS | 353.484 | 4 / 0 | 3.8 | Yes |
| 59371 |  CHEMBL311150 | C29H34N4O3 | 486.616 | 5 / 1 | 4.1 | Yes |
| 59699 |  CHEMBL62366 | C20H20N4S | 348.468 | 4 / 0 | 4.8 | Yes |
| 60493 |  S 14489 | C22H26N2O2 | 350.462 | 4 / 0 | 3.3 | Yes |
| 62203 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 62317 |  CHEMBL51888 | C22H30N2O4S | 418.552 | 6 / 1 | 3.9 | Yes |
| 62506 |  CHEMBL52438 | C19H25NO | 283.415 | 2 / 0 | 5.1 | No |
| 63077 |  CHEMBL11592 | C26H38N2O4 | 442.6 | 5 / 0 | 4.6 | Yes |
| 65418 |  CHEMBL279320 | C27H36FN5O3 | 497.615 | 6 / 3 | 3.4 | Yes |
| 67036 |  CHEMBL65669 | C20H20N4S | 348.468 | 4 / 0 | 4.8 | Yes |
| 68901 |  CHEMBL349824 | C16H21NO2 | 259.349 | 3 / 0 | 2.8 | Yes |
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