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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL53195
Molecular formula	C32H35N7
IUPAC name	7,12-bis(4-benzylpiperazin-1-yl)-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene
Molecular weight	517.681
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.6
Synonyms	SCHEMBL8570453 BDBM50408169
Inchi Key	DEMZYMHKNNMIGU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H35N7/c1-3-8-26(9-4-1)24-35-16-20-37(21-17-35)30-14-13-28-31(34-30)39-15-7-12-29(39)32(33-28)38-22-18-36(19-23-38)25-27-10-5-2-6-11-27/h1-15H,16-25H2
PubChem CID	10553922
ChEMBL	CHEMBL53195
IUPHAR	N/A
BindingDB	50408169
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
57909	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
57911	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
57912	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
57913	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
57910	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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