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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL50188
Molecular formula	C25H36N2O4
IUPAC name	8-[3-[(5-methoxy-3,4-dihydro-2H-chromen-3-yl)-propylamino]propyl]-8-azaspiro[4.5]decane-7,9-dione
Molecular weight	428.573
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.2
Synonyms	8-{3-[(5-Methoxy-chroman-3-yl)-propyl-amino]-propyl}-8-aza-spiro[4.5]decane-7,9-dione; compound with oxalic acid CHEMBL27650 BDBM50036856 8-[3-[[(5-Methoxy-3,4-dihydro-2H-1-benzopyran)-3-yl]propylamino]propyl]-8-azaspiro[4.5]decane-7,9-dione
Inchi Key	AGKVXTQIBHAKGE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H36N2O4/c1-3-12-26(19-15-20-21(30-2)8-6-9-22(20)31-18-19)13-7-14-27-23(28)16-25(17-24(27)29)10-4-5-11-25/h6,8-9,19H,3-5,7,10-18H2,1-2H3
PubChem CID	10252000
ChEMBL	CHEMBL27650
IUPHAR	N/A
BindingDB	50036856
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4973	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
4976	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
4971	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
4975	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
4974	Alpha-2A adrenergic receptor	Q28838	ADRA2A	Bos taurus (Bovine)	452
4972	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
4977	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444

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