You can:
| Name | Alpha-1A adrenergic receptor |
|---|---|
| Species | Bos taurus (Bovine) |
| Gene | ADRA1A |
| Synonym | Alpha-1A adrenoceptor Alpha-1A adrenoreceptor Alpha-1C adrenergic receptor |
| Disease | N/A for non-human GPCRs |
| Length | 466 |
| Amino acid sequence | MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRKQSSKHTLGYTLHAPSHVLEGQHKDLVRIPVGSAETFYKISKTDGVCEWKIFSSLPRGSARMAVARDPSACTTARVRSKSFLQVCCCLGPSTPSHGENHQIPTIKIHTISLSENGEEV |
| UniProt | P18130 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4892 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 1635 |  CHEMBL1259079 | C26H28N2S | 400.584 | 3 / 0 | 5.7 | No |
| 4219 |  CHEMBL25984 | C15H23NO | 233.355 | 2 / 0 | 3.8 | Yes |
| 4975 |  CHEMBL50188 | C25H36N2O4 | 428.573 | 5 / 0 | 4.2 | Yes |
| 5548 |  CHEMBL50722 | C25H36N2O5 | 444.572 | 6 / 0 | 4.3 | Yes |
| 5560 |  CHEMBL18270 | C11H14N2 | 174.247 | 2 / 0 | 1.1 | Yes |
| 5920 |  CHEMBL50722 | C27H38N2O9 | 534.606 | 10 / 2 | N/A | No |
| 6839 |  CHEMBL1259231 | C23H26N4S | 390.549 | 4 / 0 | 3.7 | Yes |
| 8118 |  CHEMBL317333 | C26H24FN5 | 425.511 | 5 / 0 | 4.0 | Yes |
| 8313 |  CHEMBL1259080 | C27H30N2S | 414.611 | 3 / 0 | 6.1 | No |
| 10049 |  Abanoquil | C22H25N3O4 | 395.459 | 7 / 1 | 3.4 | Yes |
| 11806 |  CHEMBL54266 | C23H32N2O4S | 432.579 | 6 / 1 | 4.3 | Yes |
| 13649 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 17894 |  Bmy-7378 | C22H31N3O3 | 385.508 | 5 / 0 | 2.8 | Yes |
| 19609 |  CHEMBL327116 | C15H19N3O2S | 305.396 | 4 / 2 | 2.1 | Yes |
| 21598 |  CHEMBL14213 | C26H28N4O3S | 476.595 | 6 / 0 | 4.1 | Yes |
| 21693 |  CHEMBL89916 | C26H39N5O2 | 453.631 | 6 / 1 | 4.4 | Yes |
| 26561 |  Rauwolscine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26588 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 28844 |  1-(3,5-dichloropyridin-2-yl)piperazine | C9H11Cl2N3 | 232.108 | 3 / 1 | 1.9 | Yes |
| 32864 |  CHEMBL1203301 | C22H26N4O5S | 458.533 | 9 / 2 | 1.8 | Yes |
| 33287 |  CHEMBL176365 | C20H21N3 | 303.409 | 2 / 0 | 2.2 | Yes |
| 33854 |  CHEMBL2325928 | C24H25FN4 | 388.49 | 3 / 0 | 4.3 | Yes |
| 37838 |  CHEMBL327527 | C27H30FN7O | 487.583 | 5 / 1 | 3.2 | Yes |
| 39214 |  CHEMBL92901 | C22H31N5O2 | 397.523 | 6 / 2 | 3.3 | Yes |
| 41315 |  CHEMBL60318 | C20H22FN3OS | 371.474 | 5 / 0 | 3.9 | Yes |
| 44149 |  CHEMBL1259158 | C25H33N3OS | 423.619 | 4 / 1 | 4.2 | Yes |
| 537249 |  DEXMEDETOMIDINE | C13H16N2 | 200.285 | 1 / 1 | 3.1 | Yes |
| 54610 |  CHEMBL48925 | C25H34N2O4 | 426.557 | 5 / 1 | 4.6 | Yes |
| 56700 |  cisapride | C23H29ClFN3O4 | 465.95 | 7 / 2 | 3.4 | Yes |
| 57188 |  CID 44350012 | C17H25N5O4 | 363.418 | 7 / 3 | N/A | N/A |
| 57406 |  CHEMBL298534 | C24H31FN2O3 | 414.521 | 5 / 1 | 4.7 | Yes |
| 59262 |  CHEMBL64167 | C20H23N3OS | 353.484 | 4 / 0 | 3.8 | Yes |
| 62213 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 62316 |  CHEMBL51888 | C22H30N2O4S | 418.552 | 6 / 1 | 3.9 | Yes |
| 62512 |  CHEMBL52438 | C19H25NO | 283.415 | 2 / 0 | 5.1 | No |
| 63083 |  CHEMBL11592 | C26H38N2O4 | 442.6 | 5 / 0 | 4.6 | Yes |
| 64414 |  CHEMBL24619 | C30H34N4O6 | 546.624 | 10 / 1 | 5.0 | No |
| 66962 |  TAMSULOSIN | C20H28N2O5S | 408.513 | 7 / 2 | 2.7 | Yes |
| 68345 |  CHEMBL1203301 | C22H27ClN4O5S | 494.991 | 9 / 3 | N/A | N/A |
| 68942 |  CHEMBL301060 | C28H40N2O8 | 532.634 | 9 / 2 | N/A | No |
| 69395 |  CHEMBL328187 | C27H30FN7O | 487.583 | 5 / 1 | 2.9 | Yes |
| 69950 |  CHEMBL93923 | C28H31FN6O | 486.595 | 4 / 1 | 3.4 | Yes |
| 71132 |  CHEMBL47471 | C16H18ClN3 | 287.791 | 3 / 0 | 3.2 | Yes |
| 71937 |  CHEMBL17926 | C11H13ClN2 | 208.689 | 2 / 0 | 1.7 | Yes |
| 72743 |  CHEMBL59741 | C20H20F3N3OS | 407.455 | 7 / 1 | 4.5 | Yes |
| 76589 |  (R)-zacopride | C15H20ClN3O2 | 309.794 | 4 / 2 | 1.7 | Yes |
| 77261 |  SDZ-205557 | C14H21ClN2O3 | 300.783 | 5 / 1 | 3.2 | Yes |
| 77709 |  CHEMBL91876 | C24H33N5O2 | 423.561 | 6 / 1 | 3.6 | Yes |
| 77776 |  CHEMBL1259188 | C27H31FN8O | 502.598 | 6 / 1 | 3.6 | No |
| 79462 |  CHEMBL156283 | C10H15N3 | 177.251 | 2 / 1 | 1.0 | Yes |
| 79510 |  CHEMBL368475 | C20H21F3N2S | 378.457 | 5 / 0 | 4.2 | Yes |
| 82722 |  87394-57-8 | C10H14ClN3 | 211.693 | 3 / 0 | 1.7 | Yes |
| 85376 |  87394-63-6 | C10H12F3N3 | 231.222 | 6 / 1 | 1.5 | Yes |
| 87885 |  CHEMBL1259062 | C26H28N2S | 400.584 | 3 / 0 | 5.7 | No |
| 88013 |  CHEMBL420997 | C25H25FN6 | 428.515 | 5 / 0 | 3.8 | Yes |
| 88084 |  CHEMBL296395 | C22H24N2O4 | 380.444 | 5 / 1 | 2.9 | Yes |
| 88219 |  CHEMBL1259042 | C23H24N4S | 388.533 | 5 / 0 | 3.6 | Yes |
| 88270 |  CHEMBL50993 | C25H36N2O3 | 412.574 | 4 / 0 | 4.6 | Yes |
| 92983 |  CHEMBL300735 | C24H34N2O4S | 446.606 | 6 / 1 | 4.6 | Yes |
| 94253 |  CHEMBL330060 | C23H32N4O2 | 396.535 | 5 / 1 | 3.9 | Yes |
| 95815 |  CHEMBL338704 | C11H14BrN5 | 296.172 | 4 / 0 | 2.0 | Yes |
| 95876 |  CHEMBL538537 | C12H18ClN5 | 267.761 | 4 / 2 | N/A | N/A |
| 538411 |  clonidine | C9H9Cl2N3 | 230.092 | 1 / 2 | 1.6 | Yes |
| 99329 |  CHEMBL368413 | C19H22N2 | 278.399 | 1 / 0 | 2.5 | Yes |
| 101634 |  5-Meo-dpac | C16H25NO2 | 263.381 | 3 / 0 | 3.8 | Yes |
| 102088 |  CHEMBL91093 | C26H39N5O2 | 453.631 | 6 / 1 | 4.9 | Yes |
| 108400 |  CHEMBL299007 | C10H14ClN3 | 211.693 | 3 / 1 | 1.6 | Yes |
| 108595 |  WB-4101 | C19H23NO5 | 345.395 | 6 / 1 | 2.9 | Yes |
| 109132 |  SERTINDOLE | C24H26ClFN4O | 440.947 | 3 / 1 | 4.1 | Yes |
| 109375 |  1-(2-Pyridyl)piperazine | C9H13N3 | 163.224 | 3 / 1 | 0.7 | Yes |
| 112354 |  CHEMBL285010 | C14H19NO2 | 233.311 | 3 / 0 | 2.5 | Yes |
| 113068 |  CHEMBL13735 | C19H22N4O3S | 386.47 | 6 / 1 | 2.2 | Yes |
| 115730 |  5-Methylurapidil | C21H31N5O3 | 401.511 | 6 / 1 | 1.9 | Yes |
| 117770 |  1-(3-chloropyridin-2-yl)piperazine | C9H12ClN3 | 197.666 | 3 / 1 | 1.3 | Yes |
| 118312 |  A-119637 | C25H26N4O3S | 462.568 | 6 / 1 | 3.9 | Yes |
| 120662 |  CHEMBL54089 | C26H30N2O8 | 498.532 | 9 / 2 | N/A | N/A |
| 120831 |  IDAZOXAN | C11H12N2O2 | 204.229 | 3 / 1 | 0.7 | Yes |
| 121140 |  1-(3-fluoropyridin-2-yl)piperazine | C9H12FN3 | 181.214 | 4 / 1 | 0.8 | Yes |
| 121544 |  CHEMBL88512 | C20H27N5O2 | 369.469 | 6 / 2 | 2.6 | Yes |
| 121672 |  CHEMBL294730 | C22H27N3O2S | 397.537 | 5 / 0 | 4.1 | Yes |
| 122583 |  1-(3-nitropyridin-2-yl)piperazine | C9H12N4O2 | 208.221 | 5 / 1 | 0.5 | Yes |
| 125278 |  CHEMBL178376 | C20H19N3 | 301.393 | 2 / 0 | 2.5 | Yes |
| 131342 |  prazosin | C19H21N5O4 | 383.408 | 8 / 1 | 2.0 | Yes |
| 561433 |  CHEMBL307364 | C10H11N5O | 217.232 | 3 / 4 | 0.3 | Yes |
| 133950 |  CHEMBL346492 | C15H17NS | 243.368 | 2 / 0 | 3.7 | Yes |
| 136069 |  CHEMBL59823 | C24H31N3O3 | 409.53 | 5 / 0 | 3.6 | Yes |
| 140507 |  CHEMBL2325931 | C24H24N4 | 368.484 | 3 / 0 | 3.7 | Yes |
| 140733 |  CHEMBL52396 | C25H30N2O4 | 422.525 | 5 / 0 | 4.3 | Yes |
| 142028 |  CHEMBL88820 | C23H30N4O3 | 410.518 | 5 / 1 | 2.6 | Yes |
| 142053 |  CHEMBL61819 | C23H29N3O2S | 411.564 | 5 / 0 | 4.4 | Yes |
| 142919 |  1',2',3',6'-Tetrahydro-[2,4']bipyridinyl | C10H12N2 | 160.22 | 2 / 1 | 0.6 | Yes |
| 143013 |  CHEMBL17605 | C11H14N2 | 174.247 | 2 / 0 | 1.1 | Yes |
| 143147 |  CHEMBL545198 | C23H26N2O4 | 394.471 | 5 / 0 | 3.6 | Yes |
| 147182 |  CHEMBL92109 | C23H33N5O | 395.551 | 5 / 1 | 3.9 | Yes |
| 148418 |  CHEMBL346016 | C11H15NS | 193.308 | 2 / 0 | 2.4 | Yes |
| 150288 |  CHEMBL366388 | C24H29FN2O | 380.507 | 4 / 0 | 4.1 | Yes |
| 152921 |  CHEMBL51985 | C27H41N2O4+ | 457.635 | 4 / 0 | 4.6 | Yes |
| 153120 |  CHEMBL545198 | C23H27ClN2O4 | 430.929 | 5 / 1 | N/A | N/A |
| 153541 |  CHEMBL1259005 | C24H26N2S2 | 406.606 | 4 / 0 | 5.4 | No |
| 159380 |  CHEMBL1259113 | C20H25N3S | 339.501 | 4 / 1 | 2.6 | Yes |
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