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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	A-119637
Molecular formula	C25H26N4O3S
IUPAC name	3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione
Molecular weight	462.568
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.9
Synonyms	3-[2-[4-(2-Methoxyphenyl)piperazino]ethyl]-5-phenyl-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-2,4-dione GTPL490 A119637 3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-5-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione CHEMBL268758 A 119637 SCHEMBL7837611 3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5-phenyl-1H-thieno[3,2-e]pyrimidine-2,4-dione BDBM50099322 D0Q7ZR [ Show all ]
Inchi Key	HLVQBOYEHQRWHG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26N4O3S/c1-32-21-10-6-5-9-20(21)28-14-11-27(12-15-28)13-16-29-24(30)22-19(18-7-3-2-4-8-18)17-33-23(22)26-25(29)31/h2-10,17H,11-16H2,1H3,(H,26,31)
PubChem CID	9890547
ChEMBL	CHEMBL268758
IUPHAR	490
BindingDB	50099322
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
118308	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
118311	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
118312	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
118305	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
118307	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
118309	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
118314	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
118306	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
118315	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
118310	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
118316	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
118313	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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