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| Name | Alpha-1B adrenergic receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Adra1b |
| Synonym | adrenergic receptor alpha 1B-adrenoceptor alpha 1B-adrenoreceptor adrenergic alpha 1B receptor Alpha-1B adrenoceptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 515 |
| Amino acid sequence | MNPDLDTGHNTSAPAHWGELKDDNFTGPNQTSSNSTLPQLDVTRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSATLEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFMRILGCQCRGGRRRRRRRRLGACAYTYRPWTRGGSLERSQSRKDSLDDSGSCMSGTQRTLPSASPSPGYLGRGTQPPVELCAFPEWKPGALLSLPEPPGRRGRLDSGPLFTFKLLGDPESPGTEGDTSNGGCDTTTDLANGQPGFKSNMPLAPGHF |
| UniProt | P15823 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL315 |
| IUPHAR | 23 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 3041 |  CHEMBL1255085 | C23H25NO5 | 395.455 | 6 / 3 | 3.9 | Yes |
| 441852 |  CHEMBL3342860 | C27H32F3N3O4 | 519.565 | 9 / 0 | 3.9 | No |
| 4500 |  CHEMBL215151 | C24H26ClNO4 | 427.925 | 5 / 2 | N/A | N/A |
| 4732 |  lipoic acid | C8H14O2S2 | 206.318 | 4 / 1 | 1.7 | Yes |
| 6906 |  CHEMBL25098 | C33H37N3O4 | 539.676 | 6 / 1 | 5.6 | No |
| 7218 |  Isoindoline, 26 | C24H28FN3O2 | 409.505 | 6 / 1 | 3.4 | Yes |
| 442023 |  CHEMBL3342852 | C19H28N2O3S | 364.504 | 6 / 0 | 2.5 | Yes |
| 8040 |  CHEMBL1259129 | C22H26N6S | 406.552 | 6 / 0 | 3.3 | Yes |
| 536199 |  CHEMBL27021 | C19H24N2O | 296.414 | 3 / 0 | 3.8 | Yes |
| 8781 |  CHEMBL220515 | C24H26ClN5O2 | 451.955 | 5 / 1 | 3.6 | Yes |
| 9552 |  GSK163090 | C25H29N5O | 415.541 | 4 / 1 | 3.4 | Yes |
| 10782 |  CHEMBL1242445 | C26H33N3O4 | 451.567 | 6 / 0 | 2.4 | Yes |
| 10785 |  CHEMBL1242444 | C26H33N3O4 | 451.567 | 6 / 0 | 2.4 | Yes |
| 442134 |  CHEMBL3415012 | C24H30N4O2 | 406.53 | 4 / 2 | 3.2 | Yes |
| 11273 |  CHEMBL1946783 | C31H34N2O6 | 530.621 | 8 / 2 | N/A | No |
| 11530 |  3-MPPI | C23H25N5O3 | 419.485 | 5 / 2 | 2.7 | Yes |
| 12630 |  CHEMBL62033 | C24H24N4O3 | 416.481 | 5 / 1 | 2.5 | Yes |
| 14228 |  180083-23-2 | C32H32N4O3 | 520.633 | 6 / 0 | 5.6 | No |
| 15010 |  EMETINE | C29H40N2O4 | 480.649 | 6 / 1 | 4.7 | Yes |
| 464810 |  CHEMBL3609357 | C24H29N3 | 359.517 | 2 / 1 | 4.1 | Yes |
| 17130 |  CHEMBL2440659 | C15H11FN4O2S | 330.337 | 7 / 1 | 2.4 | Yes |
| 17891 |  Bmy-7378 | C22H31N3O3 | 385.508 | 5 / 0 | 2.8 | Yes |
| 19140 |  CHEMBL1255003 | C25H29NO3 | 391.511 | 4 / 1 | 5.3 | No |
| 442421 |  CHEMBL3415013 | C25H32N4O2 | 420.557 | 4 / 2 | 3.5 | Yes |
| 22961 |  CHEMBL382972 | C26H31NO5 | 437.536 | 6 / 1 | 4.9 | Yes |
| 442603 |  CHEMBL3342872 | C23H31N3O5S2 | 493.637 | 9 / 0 | 2.7 | Yes |
| 25048 |  CHEMBL42231 | C27H31NO3 | 417.549 | 4 / 1 | 5.5 | No |
| 26042 |  LISURIDE | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 26611 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26947 |  terconazole | C26H31Cl2N5O3 | 532.466 | 7 / 0 | 4.8 | No |
| 27752 |  BDBM29566 | C21H26F3N3O2 | 409.453 | 7 / 0 | 3.5 | Yes |
| 28376 |  sildenafil | C22H30N6O4S | 474.58 | 8 / 1 | 1.5 | Yes |
| 29366 |  CHEMBL2153559 | C20H25NO6 | 375.421 | 7 / 1 | 2.9 | Yes |
| 442824 |  CHEMBL3415017 | C23H27BrN4O2 | 471.399 | 4 / 2 | 4.3 | Yes |
| 30122 |  CHEMBL495289 | C25H27NO3 | 389.495 | 4 / 1 | 4.0 | Yes |
| 442844 |  CHEMBL3342856 | C19H29N3O3 | 347.459 | 6 / 1 | 1.4 | Yes |
| 442866 |  CHEMBL3342855 | C19H28N2O5S | 396.502 | 7 / 0 | 1.2 | Yes |
| 442995 |  CHEMBL3342866 | C25H33N3O5S | 487.615 | 8 / 0 | 2.7 | Yes |
| 34098 |  Isoindoline, 8 | C23H26FN3O2 | 395.478 | 6 / 1 | 2.9 | Yes |
| 443023 |  CHEMBL3342873 | C20H31N3O5S | 425.544 | 8 / 0 | 1.1 | Yes |
| 34925 |  CHEMBL385371 | C26H30ClNO4 | 455.979 | 5 / 2 | N/A | N/A |
| 37294 |  Isoindoline, 23 | C23H24FN3O3 | 409.461 | 6 / 1 | 2.5 | Yes |
| 37874 |  Pecazine | C19H22N2S | 310.459 | 3 / 0 | 5.6 | No |
| 38247 |  CHEMBL541129 | C21H32Cl2FN3 | 416.406 | 3 / 3 | N/A | N/A |
| 40979 |  CHEMBL145384 | C26H34ClN5O3 | 500.04 | 7 / 1 | 4.6 | No |
| 41109 |  CHEMBL1946781 | C28H29NO6 | 475.541 | 7 / 3 | N/A | N/A |
| 41695 |  L-765314 | C27H34N6O5 | 522.606 | 9 / 2 | 3.1 | No |
| 43921 |  CHEMBL388884 | C23H26BrN5O4 | 516.396 | 8 / 1 | 4.4 | No |
| 47784 |  CHEMBL1630940 | C20H25F3N2O5S | 462.484 | 10 / 2 | 3.5 | Yes |
| 47954 |  CHEMBL2153551 | C19H23NO6 | 361.394 | 7 / 2 | 2.5 | Yes |
| 48026 |  CHEMBL2153555 | C19H22ClNO5 | 379.837 | 6 / 1 | 3.5 | Yes |
| 48874 |  CHEMBL38634 | C20H23NO | 293.41 | 2 / 0 | 4.2 | Yes |
| 49887 |  CHEMBL537428 | C21H31N3 | 325.5 | 2 / 1 | 3.9 | Yes |
| 50172 |  CHEMBL121943 | C22H22F3N5O3 | 461.445 | 10 / 1 | 3.5 | Yes |
| 50748 |  levomedetomidine | C13H16N2 | 200.285 | 1 / 1 | 3.1 | Yes |
| 54775 |  CHEMBL2153423 | C20H25ClN2O3 | 376.881 | 5 / 1 | N/A | N/A |
| 55298 |  CHEMBL42472 | C26H29NO4 | 419.521 | 5 / 1 | 5.0 | Yes |
| 56693 |  cisapride | C23H29ClFN3O4 | 465.95 | 7 / 2 | 3.4 | Yes |
| 553521 |  midazolam | C18H13ClFN3 | 325.771 | 3 / 0 | 2.5 | Yes |
| 57826 |  CHEMBL138681 | C34H53N7O3 | 607.844 | 9 / 2 | 5.0 | No |
| 58098 |  cinnarizine | C26H28N2 | 368.524 | 2 / 0 | 5.8 | No |
| 60063 |  CHEMBL1946780 | C30H34N2O6 | 518.61 | 8 / 2 | N/A | No |
| 553546 |  lorazepam | C15H10Cl2N2O2 | 321.157 | 3 / 2 | 2.4 | Yes |
| 61764 |  CID 10621591 | C20H26ClNO6 | 411.879 | 7 / 1 | N/A | N/A |
| 62236 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 63150 |  (-)-Norephedrine | C9H13NO | 151.209 | 2 / 2 | 0.8 | Yes |
| 63156 |  phenylpropanolamine | C9H13NO | 151.209 | 2 / 2 | 0.8 | Yes |
| 65096 |  CID 10983860 | C27H29NO8 | 495.528 | 8 / 2 | N/A | N/A |
| 66959 |  TAMSULOSIN | C20H28N2O5S | 408.513 | 7 / 2 | 2.7 | Yes |
| 67584 |  CHEMBL372222 | C25H26ClN5O2 | 463.966 | 4 / 2 | 4.0 | Yes |
| 68108 |  CHEMBL493283 | C26H29NO4 | 419.521 | 5 / 1 | 4.0 | Yes |
| 68187 |  CID 10915913 | C19H27NO7 | 381.425 | 7 / 2 | N/A | N/A |
| 68795 |  SNAP-7915 | C25H28F3N3O3 | 475.512 | 7 / 1 | 5.0 | Yes |
| 68891 |  UPIDOSIN | C31H33N3O4 | 511.622 | 6 / 1 | 4.8 | No |
| 70359 |  CHEMBL2092927 | C23H27N5OS | 421.563 | 6 / 0 | 3.2 | Yes |
| 70361 |  CHEMBL1788223 | C23H27N5OS | 421.563 | 6 / 0 | 3.2 | Yes |
| 70370 |  SCHEMBL5674428 | C23H27N5OS | 421.563 | 6 / 0 | 3.2 | Yes |
| 70959 |  CHEMBL2261355 | C15H19N3O2S | 305.396 | 4 / 2 | 2.1 | Yes |
| 73094 |  CHEMBL1254742 | C27H33NO5 | 451.563 | 6 / 1 | 5.3 | No |
| 73275 |  CHEMBL2079655 | C19H28N6O3 | 388.472 | 8 / 3 | 1.3 | Yes |
| 73278 |  CHEMBL19376 | C19H28N6O3 | 388.472 | 8 / 3 | 1.3 | Yes |
| 74223 |  CHEMBL1946782 | C29H31NO7 | 505.567 | 8 / 3 | N/A | No |
| 74311 |  CHEMBL521665 | C20H25NO4 | 343.423 | 5 / 1 | 2.5 | Yes |
| 74320 |  CHEMBL494908 | C20H25NO4 | 343.423 | 5 / 1 | 2.5 | Yes |
| 75301 |  CHEMBL125604 | C22H25N5O3 | 407.474 | 7 / 1 | 3.0 | Yes |
| 78179 |  domperidone | C22H24ClN5O2 | 425.917 | 3 / 2 | 3.9 | Yes |
| 444791 |  CHEMBL3342858 | C24H32N4O3 | 424.545 | 7 / 0 | 2.9 | Yes |
| 444929 |  CHEMBL3415016 | C23H27N5O4 | 437.5 | 6 / 2 | 3.4 | Yes |
| 444991 |  CHEMBL3342874 | C26H34N4O4 | 466.582 | 6 / 1 | 2.7 | Yes |
| 82683 |  CHEMBL29907 | C19H23N5O4S2 | 449.544 | 10 / 3 | 2.6 | Yes |
| 84151 |  CHEMBL144677 | C26H34ClN5O3 | 500.04 | 7 / 1 | 4.6 | No |
| 84314 |  SPIPETHIANE | C20H23NS | 309.471 | 2 / 0 | 4.7 | Yes |
| 85396 |  CHEMBL2261605 | C23H27BrClN5O4 | 552.854 | 8 / 2 | N/A | No |
| 85457 |  CHEMBL537651 | C23H35N3 | 353.554 | 2 / 1 | 4.6 | Yes |
| 86281 |  CHEMBL1203228 | C62H89ClN14O6 | 1161.94 | 18 / 7 | N/A | No |
| 86700 |  CHEMBL143026 | C24H24F3N3O3 | 459.469 | 8 / 2 | 4.3 | Yes |
| 87113 |  3,8-dibromoboldine | C19H19Br2NO4 | 485.172 | 5 / 2 | 4.1 | Yes |
| 87195 |  CHEMBL111554 | C14H17N3O2S | 291.369 | 4 / 2 | 1.7 | Yes |
| 88070 |  CHEMBL111463 | C15H19N3O2S | 305.396 | 4 / 1 | 1.9 | Yes |
| 88567 |  CHEMBL215188 | C23H26ClNO5 | 431.913 | 6 / 2 | N/A | N/A |
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