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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2153551
Molecular formula	C19H23NO6
IUPAC name	(3S)-3-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-2,3-dihydro-1,4-benzodioxin-5-ol
Molecular weight	361.394
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	2.5
Synonyms	CHEMBL2221145 BDBM50392639
Inchi Key	CQDKZYPQPMHYAR-ZDUSSCGKSA-N
Inchi ID	InChI=1S/C19H23NO6/c1-22-15-6-4-7-16(23-2)19(15)24-10-9-20-11-13-12-25-17-8-3-5-14(21)18(17)26-13/h3-8,13,20-21H,9-12H2,1-2H3/t13-/m0/s1
PubChem CID	71454865
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50392639
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
47957	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
47952	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
47958	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
47954	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
47956	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
47953	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
47955	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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