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| Name | Alpha-1D adrenergic receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Adra1d |
| Synonym | ADRA1A Gpcr8 Adra-1 alpha1D-AR alpha1D-adrenoceptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 561 |
| Amino acid sequence | MTFRDILSVTFEGPRSSSSTGGSGAGGGAGTVGPEGGAVGGVPGATGGGAVVGTGSGEDNQSSTGEPGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRIHCRGAATSAKGYPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRLWAVYGHHWRASTGDARSDCAPSPRIAPPGAPLALTAHPGAGSADTPETQDSVSSSRKPASALREWRLLGPLQRPTTQLRAKVSSLSHKIRSGARRAETACALRSEVEAVSLNVPQDGAEAVICQAYEPGDYSNLRETDI |
| UniProt | P23944 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL326 |
| IUPHAR | 24 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 1129 |  CHEMBL287965 | C24H24N4O3S | 448.541 | 6 / 1 | 3.1 | Yes |
| 1637 |  CHEMBL1259079 | C26H28N2S | 400.584 | 3 / 0 | 5.7 | No |
| 2113 |  CHEMBL91326 | C24H34N4O2 | 410.562 | 5 / 1 | 4.2 | Yes |
| 3037 |  CHEMBL1255085 | C23H25NO5 | 395.455 | 6 / 3 | 3.9 | Yes |
| 441851 |  CHEMBL3342860 | C27H32F3N3O4 | 519.565 | 9 / 0 | 3.9 | No |
| 4282 |  CHEMBL65846 | C18H16N2O3 | 308.337 | 4 / 1 | 1.7 | Yes |
| 4506 |  CHEMBL215151 | C24H26ClNO4 | 427.925 | 5 / 2 | N/A | N/A |
| 4733 |  lipoic acid | C8H14O2S2 | 206.318 | 4 / 1 | 1.7 | Yes |
| 6841 |  CHEMBL1259231 | C23H26N4S | 390.549 | 4 / 0 | 3.7 | Yes |
| 442024 |  CHEMBL3342852 | C19H28N2O3S | 364.504 | 6 / 0 | 2.5 | Yes |
| 8117 |  CHEMBL317333 | C26H24FN5 | 425.511 | 5 / 0 | 4.0 | Yes |
| 8314 |  CHEMBL1259080 | C27H30N2S | 414.611 | 3 / 0 | 6.1 | No |
| 8455 |  CHEMBL208355 | C21H14ClN3O3 | 391.811 | 4 / 0 | 4.8 | Yes |
| 8641 |  CHEMBL55629 | C22H27F3N4O3 | 452.478 | 8 / 1 | 2.9 | Yes |
| 536198 |  CHEMBL27021 | C19H24N2O | 296.414 | 3 / 0 | 3.8 | Yes |
| 8783 |  CHEMBL220515 | C24H26ClN5O2 | 451.955 | 5 / 1 | 3.6 | Yes |
| 8901 |  Ethanesulfonamide, N-[3-(3-pyrrolidinyl)phenyl]- | C12H18N2O2S | 254.348 | 4 / 2 | 1.0 | Yes |
| 10046 |  Abanoquil | C22H25N3O4 | 395.459 | 7 / 1 | 3.4 | Yes |
| 10442 |  SB 204070 hydrochloride | C19H27ClN2O4 | 382.885 | 6 / 1 | 3.5 | Yes |
| 10778 |  CHEMBL1242445 | C26H33N3O4 | 451.567 | 6 / 0 | 2.4 | Yes |
| 10788 |  CHEMBL1242444 | C26H33N3O4 | 451.567 | 6 / 0 | 2.4 | Yes |
| 442133 |  CHEMBL3415012 | C24H30N4O2 | 406.53 | 4 / 2 | 3.2 | Yes |
| 11101 |  CHEMBL2261352 | C14H18N4O2 | 274.324 | 3 / 4 | 0.0 | Yes |
| 11276 |  CHEMBL1946783 | C31H34N2O6 | 530.621 | 8 / 2 | N/A | No |
| 442153 |  3-MPPI | C23H25N5O3 | 419.485 | 5 / 2 | 2.7 | Yes |
| 12628 |  CHEMBL62033 | C24H24N4O3 | 416.481 | 5 / 1 | 2.5 | Yes |
| 12757 |  CHEMBL327168 | C24H30N6O2 | 434.544 | 7 / 1 | 3.2 | Yes |
| 13574 |  CHEMBL91989 | C27H32F3N5O2 | 515.581 | 9 / 1 | 5.3 | No |
| 13674 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 13975 |  CHEMBL57364 | C21H28ClN3O2 | 389.924 | 4 / 0 | 3.5 | Yes |
| 14974 |  CHEMBL434591 | C25H25N3O3S | 447.553 | 5 / 1 | 4.2 | Yes |
| 15286 |  CHEMBL1256344 | C34H40N4O6 | 600.716 | 8 / 1 | 4.2 | No |
| 15339 |  CHEMBL291305 | C26H32N2O4 | 436.552 | 5 / 0 | 3.5 | Yes |
| 15926 |  CHEMBL40819 | C25H24N4O5S | 492.55 | 7 / 1 | 4.0 | Yes |
| 16275 |  CHEMBL88181 | C23H31N3O2S | 413.58 | 5 / 0 | 3.9 | Yes |
| 16691 |  CHEMBL303988 | C25H31N3O4 | 437.54 | 6 / 1 | 3.4 | Yes |
| 16922 |  CHEMBL53675 | C21H26F4N4O3 | 458.458 | 9 / 1 | 3.2 | Yes |
| 17174 |  CHEMBL56150 | C21H27Cl2N3O2 | 424.366 | 4 / 0 | 4.1 | Yes |
| 17887 |  Bmy-7378 | C22H31N3O3 | 385.508 | 5 / 0 | 2.8 | Yes |
| 18754 |  CHEMBL59033 | C19H25ClN2O3 | 364.87 | 4 / 1 | 3.1 | Yes |
| 19142 |  CHEMBL1255003 | C25H29NO3 | 391.511 | 4 / 1 | 5.3 | No |
| 442420 |  CHEMBL3415013 | C25H32N4O2 | 420.557 | 4 / 2 | 3.5 | Yes |
| 19608 |  CHEMBL327116 | C15H19N3O2S | 305.396 | 4 / 2 | 2.1 | Yes |
| 21540 |  CHEMBL40780 | C26H24N4O3S | 472.563 | 6 / 1 | 3.9 | Yes |
| 21596 |  CHEMBL14213 | C26H28N4O3S | 476.595 | 6 / 0 | 4.1 | Yes |
| 21692 |  CHEMBL89916 | C26H39N5O2 | 453.631 | 6 / 1 | 4.4 | Yes |
| 22769 |  CHEMBL294705 | C23H32N4O4 | 428.533 | 6 / 0 | 3.5 | Yes |
| 22962 |  CHEMBL382972 | C26H31NO5 | 437.536 | 6 / 1 | 4.9 | Yes |
| 23013 |  CHEMBL417890 | C25H25N3O4 | 431.492 | 5 / 1 | 3.5 | Yes |
| 442608 |  CHEMBL3342872 | C23H31N3O5S2 | 493.637 | 9 / 0 | 2.7 | Yes |
| 25049 |  CHEMBL42231 | C27H31NO3 | 417.549 | 4 / 1 | 5.5 | No |
| 26548 |  Rauwolscine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26620 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 28220 |  CHEMBL209043 | C17H15ClN2O | 298.77 | 2 / 0 | 3.8 | Yes |
| 28651 |  CHEMBL313775 | C25H32F3N7O2 | 519.573 | 10 / 2 | 4.1 | No |
| 29369 |  CHEMBL2153559 | C20H25NO6 | 375.421 | 7 / 1 | 2.9 | Yes |
| 442823 |  CHEMBL3415017 | C23H27BrN4O2 | 471.399 | 4 / 2 | 4.3 | Yes |
| 30038 |  Histaprodifen | C20H23N3 | 305.425 | 2 / 2 | 3.5 | Yes |
| 30119 |  CHEMBL495289 | C25H27NO3 | 389.495 | 4 / 1 | 4.0 | Yes |
| 30254 |  CHEMBL111372 | C14H17N3O3S | 307.368 | 5 / 3 | 1.4 | Yes |
| 442843 |  CHEMBL3342856 | C19H29N3O3 | 347.459 | 6 / 1 | 1.4 | Yes |
| 30343 |  CHEMBL293539 | C21H27ClFN3O2 | 407.914 | 5 / 0 | 3.6 | Yes |
| 442871 |  CHEMBL3342855 | C19H28N2O5S | 396.502 | 7 / 0 | 1.2 | Yes |
| 32034 |  CHEMBL88160 | C26H34F3N7O2 | 533.6 | 10 / 1 | 4.3 | No |
| 442997 |  CHEMBL3342866 | C25H33N3O5S | 487.615 | 8 / 0 | 2.7 | Yes |
| 34116 |  CHEMBL417954 | C19H21F5N4O3 | 448.394 | 10 / 1 | 2.7 | Yes |
| 34215 |  CHEMBL58384 | C21H27ClIN3O2 | 515.82 | 4 / 0 | 4.1 | No |
| 443025 |  CHEMBL3342873 | C20H31N3O5S | 425.544 | 8 / 0 | 1.1 | Yes |
| 443063 |  CHEMBL385371 | C26H30ClNO4 | 455.979 | 5 / 2 | N/A | N/A |
| 35800 |  CHEMBL299454 | C21H30ClN3O | 375.941 | 3 / 0 | 4.1 | Yes |
| 36163 |  CHEMBL433348 | C23H30N4O2 | 394.519 | 6 / 1 | 3.8 | Yes |
| 37102 |  CHEMBL2115086 | C21H23N3O3S | 397.493 | 5 / 1 | 2.8 | Yes |
| 37104 |  CHEMBL291839 | C21H23N3O3S | 397.493 | 5 / 1 | 2.8 | Yes |
| 37111 |  CHEMBL55460 | C20H27Cl2N3O2 | 412.355 | 4 / 1 | 4.2 | Yes |
| 37835 |  CHEMBL327527 | C27H30FN7O | 487.583 | 5 / 1 | 3.2 | Yes |
| 39216 |  CHEMBL92901 | C22H31N5O2 | 397.523 | 6 / 2 | 3.3 | Yes |
| 39301 |  CHEMBL61598 | C25H28N4O4 | 448.523 | 5 / 2 | 2.0 | Yes |
| 39637 |  CHEMBL207950 | C23H20N2O3 | 372.424 | 4 / 0 | 4.3 | Yes |
| 40566 |  CHEMBL56375 | C20H26F4N4O5 | 478.445 | 11 / 3 | 1.3 | No |
| 40980 |  CHEMBL145384 | C26H34ClN5O3 | 500.04 | 7 / 1 | 4.6 | No |
| 41107 |  CHEMBL1946781 | C28H29NO6 | 475.541 | 7 / 3 | N/A | N/A |
| 41696 |  L-765314 | C27H34N6O5 | 522.606 | 9 / 2 | 3.1 | No |
| 43923 |  CHEMBL388884 | C23H26BrN5O4 | 516.396 | 8 / 1 | 4.4 | No |
| 44151 |  CHEMBL1259158 | C25H33N3OS | 423.619 | 4 / 1 | 4.2 | Yes |
| 44751 |  CHEMBL60510 | C25H29N3O3 | 419.525 | 4 / 1 | 3.5 | Yes |
| 45053 |  CHEMBL503007 | C32H36N4O6 | 572.662 | 8 / 1 | 3.4 | No |
| 47782 |  CHEMBL1630940 | C20H25F3N2O5S | 462.484 | 10 / 2 | 3.5 | Yes |
| 47832 |  CHEMBL62109 | C24H26ClN3O4 | 455.939 | 5 / 1 | 3.4 | Yes |
| 47955 |  CHEMBL2153551 | C19H23NO6 | 361.394 | 7 / 2 | 2.5 | Yes |
| 48023 |  CHEMBL2153555 | C19H22ClNO5 | 379.837 | 6 / 1 | 3.5 | Yes |
| 48858 |  CHEMBL293674 | C17H16N2O2 | 280.327 | 3 / 0 | 2.8 | Yes |
| 48917 |  CHEMBL57797 | C20H25Cl2N3O3 | 426.338 | 4 / 1 | 3.4 | Yes |
| 49287 |  CHEMBL60699 | C29H38N4O3 | 490.648 | 6 / 0 | 2.9 | Yes |
| 49598 |  CHEMBL330579 | C23H30F3N5O2 | 465.521 | 9 / 1 | 4.3 | Yes |
| 49944 |  CHEMBL302192 | C25H33N3O3 | 423.557 | 6 / 1 | 3.7 | Yes |
| 50174 |  CHEMBL121943 | C22H22F3N5O3 | 461.445 | 10 / 1 | 3.5 | Yes |
| 50706 |  CHEMBL66432 | C16H14N2O2 | 266.3 | 3 / 1 | 2.6 | Yes |
| 53381 |  CHEMBL299691 | C21H28FN3O2 | 373.472 | 5 / 0 | 2.9 | Yes |
| 53648 |  CHEMBL327351 | C22H31N5O3 | 413.522 | 7 / 2 | 2.8 | Yes |
| 54379 |  CHEMBL301650 | C20H22F6N4O3 | 480.411 | 11 / 1 | 3.2 | No |
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