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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL382972
Molecular formula	C26H31NO5
IUPAC name	N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(2-methylphenyl)methoxy]phenoxy]ethanamine
Molecular weight	437.536
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.9
Synonyms	N/A
Inchi Key	BGFYEOBLDYCILL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H31NO5/c1-20-9-4-5-10-21(20)19-32-23-12-7-6-11-22(23)30-17-15-27-16-18-31-26-24(28-2)13-8-14-25(26)29-3/h4-14,27H,15-19H2,1-3H3
PubChem CID	11539392
ChEMBL	CHEMBL382972
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22959	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
22956	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
22960	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
22957	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
22961	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
22958	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
22962	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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