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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL27021
Molecular formula	C19H24N2O
IUPAC name	1-(2-methoxyphenyl)-4-(2-phenylethyl)piperazine
Molecular weight	296.414
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.8
Synonyms	144146-62-3 CTK0B3508 SMR000496368 ACMC-20n3n3 MLS001001194 ZINC5586934 1-(2-methoxyphenyl)-4-(2-phenylethyl)piperazine Piperazine, 1-(2-methoxyphenyl)-4-(2-phenylethyl)- DTXSID80396958 SR-01000208947 AMBPIKSQPHQYTQ-UHFFFAOYSA-N MolPort-002-149-742 1-(2-methoxyphenyl)-4-phenethylpiperazine SCHEMBL5442134 AC1MY5GA HMS2828N12 SR-01000208947-1 1-(2-methoxyphenyl)-4-(2-phenyl-1-ethyl)piperazine BDBM50201787 Oprea1_554439 [ Show all ]
Inchi Key	AMBPIKSQPHQYTQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H24N2O/c1-22-19-10-6-5-9-18(19)21-15-13-20(14-16-21)12-11-17-7-3-2-4-8-17/h2-10H,11-16H2,1H3
PubChem CID	3826471
ChEMBL	CHEMBL27021
IUPHAR	N/A
BindingDB	50201787
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8728	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
536196	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
536200	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
536199	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
536201	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
536197	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
536198	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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