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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Alpha-1A adrenergic receptor
Species	Rattus norvegicus (Rat)
Gene	Adra1a
Synonym	alpha1c alpha1A-adrenoceptor alpha1a Alpha-1C adrenergic receptor Alpha-1A adrenoreceptor Alpha-1A adrenoceptor alpha-1A adrenergic receptor ADRA1C alpha 1C-adrenergic receptor alpha 1A-adrenoreceptor alpha 1A-adrenoceptor adrenergic receptor, alpha 1a adrenergic receptor alpha 1c adrenergic alpha 1c receptor ADRA1L1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	466
Amino acid sequence	MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
UniProt	P43140
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL319
IUPHAR	22
DrugBank	N/A

Ligand

Name	CHEMBL27021
Molecular formula	C19H24N2O
IUPAC name	1-(2-methoxyphenyl)-4-(2-phenylethyl)piperazine
Molecular weight	296.414
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.8
Synonyms	AC1MY5GA HMS2828N12 SR-01000208947-1 BDBM50201787 Oprea1_554439 1-(2-methoxyphenyl)-4-(2-phenyl-1-ethyl)piperazine CTK0B3508 SMR000496368 144146-62-3 ACMC-20n3n3 MLS001001194 ZINC5586934 Piperazine, 1-(2-methoxyphenyl)-4-(2-phenylethyl)- 1-(2-methoxyphenyl)-4-(2-phenylethyl)piperazine DTXSID80396958 SR-01000208947 AMBPIKSQPHQYTQ-UHFFFAOYSA-N MolPort-002-149-742 SCHEMBL5442134 1-(2-methoxyphenyl)-4-phenethylpiperazine [ Show all ]
Inchi Key	AMBPIKSQPHQYTQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H24N2O/c1-22-19-10-6-5-9-18(19)21-15-13-20(14-16-21)12-11-17-7-3-2-4-8-17/h2-10H,11-16H2,1H3
PubChem CID	3826471
ChEMBL	CHEMBL27021
IUPHAR	N/A
BindingDB	50201787
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
pKb	7.76 -	PMID27448917	ChEMBL

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