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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL88160
Molecular formula	C26H34F3N7O2
IUPAC name	N,N,1,3-tetramethyl-4-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propylamino]pyrazolo[3,4-b]pyridine-5-carboxamide
Molecular weight	533.6
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	4.3
Synonyms	BDBM50408199 N,N,1,3-Tetramethyl-4-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazino]propylamino]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Inchi Key	BSUZYOKJXFBXNY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H34F3N7O2/c1-18-22-23(19(25(37)33(2)3)16-31-24(22)34(4)32-18)30-10-7-11-35-12-14-36(15-13-35)20-8-5-6-9-21(20)38-17-26(27,28)29/h5-6,8-9,16H,7,10-15,17H2,1-4H3,(H,30,31)
PubChem CID	9893282
ChEMBL	CHEMBL88160
IUPHAR	N/A
BindingDB	50408199
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
32030	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
32031	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
32034	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
32033	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
32032	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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