You can:
| Name | 5-hydroxytryptamine receptor 1A |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Htr1a |
| Synonym | 5-HT-1A Gpcr18 ADRBRL1 ADRB2RL1 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 421 |
| Amino acid sequence | MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR |
| UniProt | Q64264 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3737 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 10041 |  CHEMBL143075 | C20H25N5OS2 | 415.574 | 7 / 2 | 3.8 | Yes |
| 10451 |  SB 204070 hydrochloride | C19H27ClN2O4 | 382.885 | 6 / 1 | 3.5 | Yes |
| 536272 |  CHEMBL3915107 | C21H23ClN2O3 | 386.876 | 4 / 0 | 3.4 | Yes |
| 557597 |  SCHEMBL14060375 | C21H23ClN2O3 | 386.876 | 4 / 0 | 3.4 | Yes |
| 10977 |  EF-7412 | C22H33N5O4S | 463.597 | 7 / 1 | 1.5 | Yes |
| 13630 |  CHEMBL26998 | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 13661 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 23245 |  DIHYDREXIDINE | C17H17NO2 | 267.328 | 3 / 3 | 2.5 | Yes |
| 24694 |  CHEMBL88365 | C17H20N2O | 268.36 | 3 / 1 | 3.0 | Yes |
| 32030 |  CHEMBL88160 | C26H34F3N7O2 | 533.6 | 10 / 1 | 4.3 | No |
| 34050 |  CHEMBL2021539 | C15H21ClF3NO2S | 371.843 | 6 / 2 | N/A | N/A |
| 34053 |  CHEMBL2021524 | C15H21ClF3NO2S | 371.843 | 6 / 2 | N/A | N/A |
| 558726 |  SCHEMBL15746093 | C22H27N3O3 | 381.476 | 5 / 0 | 2.5 | Yes |
| 537187 |  CHEMBL3941579 | C22H27N3O3 | 381.476 | 5 / 0 | 2.5 | Yes |
| 548425 |  CHEMBL3935152 | C22H27N3O3 | 381.476 | 5 / 0 | 2.5 | Yes |
| 558729 |  SCHEMBL15746091 | C22H27N3O3 | 381.476 | 5 / 0 | 2.5 | Yes |
| 548427 |  CHEMBL3956749 | C22H27N3O3 | 381.476 | 5 / 0 | 2.5 | Yes |
| 558731 |  SCHEMBL15746095 | C22H27N3O3 | 381.476 | 5 / 0 | 2.5 | Yes |
| 64668 |  PD-168077 | C20H22N4O | 334.423 | 4 / 1 | 3.0 | Yes |
| 559424 |  SCHEMBL14061923 | C20H25N3O2 | 339.439 | 5 / 0 | 2.7 | Yes |
| 548693 |  CHEMBL3969837 | C20H25N3O2 | 339.439 | 5 / 0 | 2.7 | Yes |
| 68781 |  SNAP-7915 | C25H28F3N3O3 | 475.512 | 7 / 1 | 5.0 | Yes |
| 78732 |  CHEMBL343838 | C23H26N6OS | 434.562 | 6 / 2 | 4.2 | Yes |
| 106802 |  CHEMBL135623 | C23H24FN3OS | 409.523 | 5 / 2 | 4.3 | Yes |
| 111883 |  CHEMBL11388 | C16H23NO | 245.366 | 2 / 0 | 3.6 | Yes |
| 114924 |  CHEMBL336842 | C23H25FN2O3S | 428.522 | 7 / 1 | 3.9 | Yes |
| 549280 |  CHEMBL3930615 | C23H28N2O3 | 380.488 | 4 / 0 | 3.5 | Yes |
| 560861 |  SCHEMBL15746098 | C23H28N2O3 | 380.488 | 4 / 0 | 3.5 | Yes |
| 121984 |  CHEMBL142211 | C21H26N6OS | 410.54 | 7 / 2 | 3.4 | Yes |
| 124415 |  CHEMBL104985 | C14H18ClN3O | 279.768 | 4 / 0 | 3.4 | Yes |
| 134690 |  CHEMBL138458 | C23H29NO2 | 351.49 | 3 / 0 | 4.3 | Yes |
| 549734 |  CHEMBL3957983 | C21H25N3O3 | 367.449 | 5 / 0 | 2.1 | Yes |
| 549735 |  CHEMBL3957263 | C21H25N3O3 | 367.449 | 5 / 0 | 2.1 | Yes |
| 561825 |  SCHEMBL15746099 | C21H25N3O3 | 367.449 | 5 / 0 | 2.1 | Yes |
| 561826 |  SCHEMBL15746100 | C21H25N3O3 | 367.449 | 5 / 0 | 2.1 | Yes |
| 146218 |  GR 103691 | C30H35N3O3 | 485.628 | 5 / 1 | 4.8 | Yes |
| 549738 |  CHEMBL3960882 | C21H25N3O3 | 367.449 | 5 / 0 | 2.4 | Yes |
| 561847 |  SCHEMBL15746101 | C21H25N3O3 | 367.449 | 5 / 0 | 2.4 | Yes |
| 148852 |  CHEMBL91605 | C25H34FN7O2 | 483.592 | 8 / 1 | 3.3 | Yes |
| 157369 |  CHEMBL143447 | C21H26N6OS | 410.54 | 7 / 2 | 3.1 | Yes |
| 540372 |  CHEMBL3900699 | C22H26N2O4 | 382.46 | 5 / 0 | 2.7 | Yes |
| 562658 |  SCHEMBL15746087 | C22H26N2O4 | 382.46 | 5 / 0 | 2.7 | Yes |
| 173681 |  CHEMBL48100 | C20H23N5O3S | 413.496 | 7 / 0 | 1.5 | Yes |
| 173682 |  CHEMBL49630 | C20H23N5O3S | 413.496 | 7 / 0 | 1.5 | Yes |
| 174806 |  CHEMBL335082 | C23H26N2O3S | 410.532 | 6 / 1 | 3.8 | Yes |
| 175664 |  sumatriptan | C14H21N3O2S | 295.401 | 4 / 2 | 0.9 | Yes |
| 185159 |  CHEMBL141494 | C21H25N5OS | 395.525 | 6 / 1 | 3.2 | Yes |
| 207507 |  CHEMBL141438 | C20H25N5OS2 | 415.574 | 7 / 2 | 4.2 | Yes |
| 209725 |  UNII-2L5SGH4CVS | C22H31N5O2 | 397.523 | 6 / 1 | 3.1 | Yes |
| 210079 |  CHEMBL128329 | C20H24N2O | 308.425 | 2 / 1 | 3.1 | Yes |
| 227647 |  CHEMBL2021525 | C15H20F3NO2S | 335.385 | 6 / 1 | 3.5 | Yes |
| 227651 |  CHEMBL2021538 | C15H20F3NO2S | 335.385 | 6 / 1 | 3.5 | Yes |
| 231918 |  CHEMBL142456 | C24H27N5OS | 433.574 | 5 / 2 | 4.4 | Yes |
| 241667 |  BDBM50078561 | C22H33N5O4S | 463.597 | 7 / 2 | 1.4 | Yes |
| 242946 |  CHEMBL131691 | C24H27N3OS | 405.56 | 5 / 2 | 4.5 | Yes |
| 245834 |  CHEMBL420620 | C22H30FN5O2 | 415.513 | 7 / 1 | 3.2 | Yes |
| 264922 |  CHEMBL141209 | C21H25NO2 | 323.436 | 3 / 0 | 3.5 | Yes |
| 543331 |  CHEMBL3946540 | C21H25ClN2O2 | 372.893 | 4 / 0 | 4.1 | Yes |
| 565790 |  SCHEMBL14060296 | C21H25ClN2O2 | 372.893 | 4 / 0 | 4.1 | Yes |
| 565815 |  SCHEMBL14061586 | C21H25N3O3 | 367.449 | 5 / 0 | 2.4 | Yes |
| 551319 |  CHEMBL3970895 | C21H25N3O3 | 367.449 | 5 / 0 | 2.4 | Yes |
| 286149 |  CHEMBL341326 | C20H24N2 | 292.426 | 1 / 1 | 4.1 | Yes |
| 289542 |  CP-293019 | C19H22F2N4O | 360.409 | 7 / 0 | 3.1 | Yes |
| 290303 |  serotonin | C10H12N2O | 176.219 | 2 / 3 | 0.2 | Yes |
| 566376 |  clozapine | C18H19ClN4 | 326.828 | 3 / 1 | 3.1 | Yes |
| 291447 |  risperidone | C23H27FN4O2 | 410.493 | 6 / 0 | 2.7 | Yes |
| 292433 |  CHEMBL339944 | C21H26N2 | 306.453 | 1 / 1 | 4.5 | Yes |
| 292638 |  CHEMBL89030 | C24H34N4O2 | 410.562 | 5 / 1 | 4.2 | Yes |
| 298473 |  CHEMBL358268 | C25H27N5OS | 445.585 | 6 / 1 | 4.5 | Yes |
| 300626 |  CHEMBL332154 | C18H18N2O2 | 294.354 | 4 / 2 | 3.0 | Yes |
| 544114 |  CHEMBL3986651 | C22H28N2O3 | 368.477 | 5 / 0 | 3.4 | Yes |
| 301737 |  CHEMBL356743 | C25H31N5OS | 449.617 | 6 / 2 | 4.7 | Yes |
| 309261 |  CHEMBL138809 | C20H23NO2 | 309.409 | 3 / 0 | 3.0 | Yes |
| 311827 |  CHEMBL38465 | C14H13N3S | 255.339 | 3 / 1 | 3.1 | Yes |
| 316951 |  CHEMBL2112696 | C24H24FN3OS | 421.534 | 6 / 1 | 4.8 | Yes |
| 320653 |  CHEMBL338310 | C21H26N2O | 322.452 | 2 / 1 | 3.5 | Yes |
| 328985 |  CHEMBL128954 | C19H25NO | 283.415 | 2 / 0 | 3.3 | Yes |
| 331151 |  IPSAPIRONE | C19H23N5O3S | 401.485 | 7 / 0 | 1.5 | Yes |
| 335154 |  CHEMBL344994 | C21H25N5OS | 395.525 | 6 / 1 | 3.5 | Yes |
| 345215 |  CHEMBL35226 | C21H29N3O | 339.483 | 4 / 1 | 4.5 | Yes |
| 346723 |  RS-100235 | C27H35ClN2O5 | 503.036 | 7 / 1 | 4.6 | No |
| 552280 |  CHEMBL3895206 | C20H23N3O3 | 353.422 | 5 / 0 | 2.0 | Yes |
| 568190 |  SCHEMBL14061894 | C20H23N3O3 | 353.422 | 5 / 0 | 2.0 | Yes |
| 348826 |  CHEMBL49623 | C21H27NO2 | 325.452 | 3 / 2 | 3.9 | Yes |
| 348840 |  Ifenprodil | C21H27NO2 | 325.452 | 3 / 2 | 3.9 | Yes |
| 351127 |  CHEMBL64508 | C15H17NO2 | 243.306 | 3 / 2 | 2.6 | Yes |
| 354121 |  CHEMBL141319 | C23H26N6OS | 434.562 | 6 / 2 | 3.8 | Yes |
| 355884 |  CHEMBL142277 | C24H29N5OS | 435.59 | 6 / 2 | 4.3 | Yes |
| 359072 |  CHEMBL63449 | C20H28N2O | 312.457 | 2 / 1 | 4.3 | Yes |
| 359075 |  CHEMBL65274 | C20H28N2O | 312.457 | 2 / 1 | 4.3 | Yes |
| 362603 |  CHEMBL10270 | C16H21NO | 243.35 | 2 / 0 | 3.2 | Yes |
| 362608 |  CHEMBL418705 | C16H21NO | 243.35 | 2 / 0 | 3.2 | Yes |
| 362618 |  CHEMBL26118 | C16H21NO | 243.35 | 2 / 0 | 3.2 | Yes |
| 366804 |  CHEMBL141392 | C21H26N6OS | 410.54 | 7 / 2 | 3.4 | Yes |
| 378988 |  CHEMBL343228 | C24H27N5OS | 433.574 | 5 / 2 | 4.4 | Yes |
| 379639 |  CHEMBL37170 | C22H27N3O | 349.478 | 3 / 1 | 3.5 | Yes |
| 379643 |  CHEMBL35093 | C22H27N3O | 349.478 | 3 / 1 | 3.5 | Yes |
| 389324 |  CHEMBL554220 | C14H19ClF3NO3S | 373.815 | 7 / 2 | N/A | N/A |
| 390724 |  CHEMBL342742 | C21H26N6OS | 410.54 | 7 / 2 | 3.1 | Yes |
| 393529 |  CHEMBL141485 | C20H25N5OS2 | 415.574 | 7 / 2 | 4.2 | Yes |
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