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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL135623
Molecular formula	C23H24FN3OS
IUPAC name	1-(5-fluoro-1-benzothiophen-3-yl)-3-[4-(1H-indol-4-yl)piperazin-1-yl]propan-1-ol
Molecular weight	409.523
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.3
Synonyms	SCHEMBL6596051 1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-[4-(1H-indol-4-yl)-piperazin-1-yl]-propan-1-ol; BDBM50118330
Inchi Key	GWCXMTRMKIIFDL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H24FN3OS/c24-16-4-5-23-18(14-16)19(15-29-23)22(28)7-9-26-10-12-27(13-11-26)21-3-1-2-20-17(21)6-8-25-20/h1-6,8,14-15,22,25,28H,7,9-13H2
PubChem CID	10158434
ChEMBL	CHEMBL135623
IUPHAR	N/A
BindingDB	50118330
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
106801	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
106802	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421

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