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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 1A
Species	Mus musculus (Mouse)
Gene	Htr1a
Synonym	5-HT-1A Gpcr18 ADRBRL1 ADRB2RL1 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 5-HT1A receptor 5-HT1A Serotonin receptor 1A [ Show all ]
Disease	N/A for non-human GPCRs
Length	421
Amino acid sequence	MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR
UniProt	Q64264
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3737
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL14061586
Molecular formula	C21H25N3O3
IUPAC name	1-(2,3-dihydroindol-1-yl)-2-[(2R)-2-[(4-methylpyridin-2-yl)oxymethyl]morpholin-4-yl]ethanone
Molecular weight	367.449
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.4
Synonyms	US9079895, 16r BDBM186924
Inchi Key	QBMBRZQSSOYRMY-GOSISDBHSA-N
Inchi ID	InChI=1S/C21H25N3O3/c1-16-6-8-22-20(12-16)27-15-18-13-23(10-11-26-18)14-21(25)24-9-7-17-4-2-3-5-19(17)24/h2-6,8,12,18H,7,9-11,13-15H2,1H3/t18-/m1/s1
PubChem CID	71062581
ChEMBL	N/A
IUPHAR	N/A
BindingDB	186924
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2298.0 nM	N/A	BindingDB

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