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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL138458
Molecular formula	C23H29NO2
IUPAC name	3-methoxy-1'-(3-phenylpropyl)spiro[3,4-dihydroisochromene-1,4'-piperidine]
Molecular weight	351.49
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.3
Synonyms	1'-(3-Phenylpropyl)-3-methoxy-3,4-dihydrospiro[1H-2-benzopyran-1,4'-piperidine] BDBM50108654 1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4''-(hexahydropyridine)]-1-yl]-3-phenylpropane
Inchi Key	IJKYJDDNDXAREJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H29NO2/c1-25-22-18-20-11-5-6-12-21(20)23(26-22)13-16-24(17-14-23)15-7-10-19-8-3-2-4-9-19/h2-6,8-9,11-12,22H,7,10,13-18H2,1H3
PubChem CID	10915140
ChEMBL	CHEMBL138458
IUPHAR	N/A
BindingDB	50108654
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
134690	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
134693	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
134695	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
134694	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
134687	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
134688	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
134691	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465
134689	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
134692	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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