You can:
| Name | Alpha-2A adrenergic receptor |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | ADRA2A |
| Synonym | alpha2D alpha2A-AR alpha2A-adrenoceptor alpha2A-adrenergic receptor alpha2A [ Show all ] |
| Disease | Attention deficit hyperactivity disorder Sexual dysfunction Pain |
| Length | 450 |
| Amino acid sequence | MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV |
| UniProt | P08913 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P08913 |
| 3D structure model | This predicted structure model is from GPCR-EXP P08913. |
| BioLiP | N/A |
| Therapeutic Target Database | T11448 |
| ChEMBL | CHEMBL1867 |
| IUPHAR | 25 |
| DrugBank | BE0000289 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 370 |  CHEMBL218675 | C24H30N4O | 390.531 | 5 / 2 | 4.3 | Yes |
| 910 |  butenafine | C23H27N | 317.476 | 1 / 0 | 6.3 | No |
| 1496 |  CHEMBL373830 | C17H18N2O2 | 282.343 | 3 / 2 | 2.6 | Yes |
| 1555 |  hexachlorophene | C13H6Cl6O2 | 406.889 | 2 / 2 | 7.5 | No |
| 1782 |  ciproxifan | C16H18N2O2 | 270.332 | 3 / 1 | 2.5 | Yes |
| 441746 |  CHEMBL329566 | C20H23NO | 293.41 | 2 / 0 | 3.6 | Yes |
| 1922 |  CHEMBL371352 | C20H23NO | 293.41 | 2 / 0 | 3.6 | Yes |
| 2260 |  1-(cyclohexylmethyl)pyrrolidine | C11H21N | 167.296 | 1 / 0 | 3.1 | Yes |
| 2406 |  CHEMBL425069 | C27H28ClN5O3 | 506.003 | 6 / 1 | 4.3 | No |
| 3143 |  AC1N0YGA | C3H7NO4S | 153.152 | 5 / 2 | -4.7 | Yes |
| 3404 |  CHEMBL1642882 | C18H19ClN4O2S | 390.886 | 5 / 3 | 3.4 | Yes |
| 3910 |  CHEMBL75491 | C12H11N5 | 225.255 | 4 / 2 | 1.6 | Yes |
| 4324 |  sulconazole | C18H15Cl3N2S | 397.742 | 2 / 0 | 6.1 | No |
| 4417 |  CHEMBL491419 | C28H33N3O4 | 475.589 | 7 / 0 | 4.0 | Yes |
| 4568 |  CHEMBL373535 | C16H17N3O | 267.332 | 3 / 1 | 1.9 | Yes |
| 4663 |  120-78-5 | C14H8N2S4 | 332.472 | 6 / 0 | 5.6 | No |
| 5057 |  BDBM50068818 | C32H39N5O6 | 589.693 | 8 / 2 | 2.9 | No |
| 5126 |  CHEMBL248272 | C26H33N3O5 | 467.566 | 7 / 1 | 3.3 | Yes |
| 5690 |  AC1L1HUK | C29H28ClN3O4 | 518.01 | 4 / 2 | 5.2 | No |
| 5773 |  paroxetine | C19H20FNO3 | 329.371 | 5 / 1 | 3.5 | Yes |
| 557467 |  CHEMBL2112969 | C25H31FN4O4 | 470.545 | 9 / 1 | 3.2 | Yes |
| 463727 |  CHEMBL3633757 | C26H24BrNO4 | 494.385 | 5 / 0 | 5.4 | No |
| 7346 |  CHEMBL179648 | C21H26N2O | 322.452 | 3 / 0 | 3.7 | Yes |
| 7402 |  CHEMBL1256610 | C15H16N2 | 224.307 | 1 / 1 | 2.9 | Yes |
| 8055 |  CHEMBL163247 | C22H19Cl2N3O2 | 428.313 | 4 / 0 | 4.0 | Yes |
| 521697 |  CHEMBL3754496 | C16H19FN2 | 258.34 | 2 / 1 | 2.9 | Yes |
| 8716 |  CHEMBL308863 | C12H15N3O2 | 233.271 | 4 / 2 | 2.2 | Yes |
| 9347 |  CHEMBL354611 | C15H18N2 | 226.323 | 1 / 1 | 2.3 | Yes |
| 9852 |  AC-42 | C20H31NO | 301.474 | 2 / 0 | 5.2 | No |
| 10447 |  SB 204070 hydrochloride | C19H27ClN2O4 | 382.885 | 6 / 1 | 3.5 | Yes |
| 10527 |  CHEMBL30739 | C13H16N2S | 232.345 | 2 / 1 | 3.2 | Yes |
| 10743 |  CHEMBL3287723 | C25H32O7 | 444.524 | 7 / 2 | 5.7 | No |
| 10985 |  CHEMBL1076586 | C26H23N3O2 | 409.489 | 2 / 1 | 4.1 | Yes |
| 11152 |  CHEMBL90966 | C27H30N4O4 | 474.561 | 8 / 0 | 3.2 | Yes |
| 11585 |  CHEMBL328377 | C27H31N3O4 | 461.562 | 7 / 0 | 3.3 | Yes |
| 521777 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 12455 |  CHEMBL1956191 | C11H13ClN2O | 224.688 | 2 / 1 | 2.0 | Yes |
| 12490 |  CHEMBL1255723 | C15H16N2 | 224.307 | 1 / 1 | 3.1 | Yes |
| 13154 |  CHEMBL1256565 | C15H16N2O | 240.306 | 2 / 1 | 1.9 | Yes |
| 13683 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 13848 |  CHEMBL554019 | C50H68N6O4 | 817.132 | 6 / 6 | 8.0 | No |
| 14233 |  180083-23-2 | C32H32N4O3 | 520.633 | 6 / 0 | 5.6 | No |
| 14626 |  CHEMBL360671 | C22H23BrF3N5O3S | 574.417 | 11 / 1 | 5.6 | No |
| 14778 |  CHEMBL1221545 | C25H31N3O3S | 453.601 | 6 / 1 | 4.5 | Yes |
| 15013 |  EMETINE | C29H40N2O4 | 480.649 | 6 / 1 | 4.7 | Yes |
| 15099 |  disulfiram | C10H20N2S4 | 296.524 | 4 / 0 | 3.9 | Yes |
| 15469 |  CHEMBL2205829 | C19H19NO3 | 309.365 | 4 / 1 | 2.2 | Yes |
| 15681 |  CHEMBL92496 | C25H31N3O4 | 437.54 | 7 / 0 | 3.4 | Yes |
| 521929 |  AM-0902 | C17H15ClN6O2 | 370.797 | 6 / 0 | 2.3 | Yes |
| 16254 |  CHEMBL328735 | C26H31N3O5 | 465.55 | 8 / 0 | 2.7 | Yes |
| 16310 |  CHEMBL217768 | C24H34N4 | 378.564 | 4 / 1 | 5.2 | No |
| 16791 |  Pipamperone | C21H30FN3O2 | 375.488 | 5 / 1 | 2.0 | Yes |
| 16882 |  Glemanserin | C20H25NO | 295.426 | 2 / 1 | 3.8 | Yes |
| 17124 |  CHEMBL2440659 | C15H11FN4O2S | 330.337 | 7 / 1 | 2.4 | Yes |
| 521987 |  CHEMBL3775473 | C23H19FN2O4S2 | 470.533 | 7 / 1 | 4.2 | Yes |
| 17449 |  SCHEMBL1276324 | C24H26F2N4O2 | 440.495 | 7 / 2 | 4.3 | Yes |
| 17580 |  CHEMBL176116 | C27H31N3O4 | 461.562 | 7 / 0 | 4.0 | Yes |
| 17944 |  CHEMBL75257 | C16H23N3O | 273.38 | 3 / 2 | 4.3 | Yes |
| 18085 |  CHEMBL112351 | C10H9F3N2O2 | 246.189 | 6 / 1 | 2.3 | Yes |
| 18666 |  CHEMBL286246 | C11H10N2S | 202.275 | 2 / 1 | 2.1 | Yes |
| 18686 |  SK&F-106686 | C14H16ClNS | 265.799 | 2 / 0 | 4.3 | Yes |
| 18987 |  CHEMBL165529 | C16H20N2 | 240.35 | 1 / 1 | 2.5 | Yes |
| 19610 |  CHEMBL327116 | C15H19N3O2S | 305.396 | 4 / 2 | 2.1 | Yes |
| 19854 |  CHEMBL521096 | C24H28FN5O2 | 437.519 | 7 / 2 | 3.9 | Yes |
| 20053 |  CHEMBL72768 | C11H14FN3S | 239.312 | 4 / 2 | 1.5 | Yes |
| 20194 |  imipramine | C19H24N2 | 280.415 | 2 / 0 | 4.8 | Yes |
| 21117 |  CHEMBL217180 | C18H24N4 | 296.418 | 4 / 1 | 3.1 | Yes |
| 21393 |  CHEMBL77913 | C11H13N3O | 203.245 | 3 / 2 | 2.3 | Yes |
| 21605 |  CHEMBL543964 | C16H16ClN3O | 301.774 | 1 / 3 | N/A | N/A |
| 21897 |  CHEMBL150161 | C20H21ClFNO2 | 361.841 | 4 / 1 | 2.9 | Yes |
| 22174 |  suloctidil | C20H35NOS | 337.566 | 3 / 2 | 5.8 | No |
| 22207 |  CHEMBL501404 | C15H12FN3O | 269.279 | 4 / 0 | 1.9 | Yes |
| 22390 |  CHEMBL1956193 | C12H13F3N2O | 258.244 | 5 / 1 | 2.2 | Yes |
| 22604 |  CHEMBL284213 | C11H12N2S | 204.291 | 2 / 1 | 2.3 | Yes |
| 23271 |  CHEMBL576623 | C14H18N2O | 230.311 | 2 / 1 | 2.4 | Yes |
| 23357 |  sulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 24244 |  CHEMBL555190 | C45H58N6O4 | 746.997 | 6 / 6 | 5.5 | No |
| 24540 |  CHEMBL1641682 | C11H13N5 | 215.26 | 2 / 3 | 0.9 | Yes |
| 25678 |  CHEMBL425012 | C23H24BrF3N4O3S | 573.429 | 10 / 2 | 6.1 | No |
| 522344 |  CHEMBL3775370 | C21H15FN2O5S | 426.418 | 7 / 1 | 2.8 | Yes |
| 26032 |  LISURIDE | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 26068 |  S-(-)-Lisuride | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 26081 |  AC1L1H1T | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 26293 |  CHEMBL600053 | C18H18FNO | 283.346 | 3 / 1 | 2.5 | Yes |
| 26354 |  CHEMBL98541 | C27H32FN3O4 | 481.568 | 8 / 0 | 4.3 | Yes |
| 26558 |  Rauwolscine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26564 |  corynanthine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26571 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26637 |  CHEBI:48565 | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26653 |  CHEMBL196400 | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26939 |  terconazole | C26H31Cl2N5O3 | 532.466 | 7 / 0 | 4.8 | No |
| 27076 |  CHEMBL258007 | C13H14N2 | 198.269 | 1 / 1 | 2.7 | Yes |
| 27223 |  CHEMBL2203713 | C18H22N4S | 326.462 | 4 / 2 | 2.9 | Yes |
| 27508 |  CHEMBL2432063 | C19H29N | 271.448 | 1 / 0 | 4.7 | Yes |
| 29579 |  xylazine | C12H16N2S | 220.334 | 2 / 1 | 2.8 | Yes |
| 29658 |  CID 10903225 | C13H20ClN3O2S | 317.832 | 5 / 2 | N/A | N/A |
| 30191 |  SCHEMBL14542291 | C22H21NO3 | 347.414 | 3 / 0 | 4.3 | Yes |
| 31087 |  CHEMBL165350 | C22H20BrN3O2 | 438.325 | 4 / 0 | 3.2 | Yes |
| 31599 |  CHEMBL214996 | C23H28N4O | 376.504 | 5 / 2 | 4.2 | Yes |
| 548256 |  CHEMBL3916901 | C25H30N2O5 | 438.524 | 6 / 0 | 2.5 | Yes |
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