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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Glemanserin
Molecular formula	C20H25NO
IUPAC name	phenyl-[1-(2-phenylethyl)piperidin-4-yl]methanol
Molecular weight	295.426
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.8
Synonyms	(1-phenethylpiperidin-4-yl)-phenylmethanol AXNGJCOYCMDPQG-UHFFFAOYSA-N D05MFO J-002002 MolPort-003-983-619 SR-01000597432-1 132553-86-7 AKOS024458672 CHEBI:91790 MDL 11,939 phenyl-[1-(2-phenylethyl)-4-piperidyl]methanol (1-Phenethyl-piperidin-4-yl)-phenyl-methanol 4-Piperidinemethanol, alpha-phenyl-1-(2-phenylethyl)-, (+-)- alpha-phenyl-[1-(2-phenylethyl)]-4-piperidinemethanol CTK8D3348 GTPL186 Mdl-11,939 SCHEMBL120012 AC1L2GSP BDBM50004327 DTXSID4042624 L002081 PDSP1_001574 ( inverted exclamation markA)-1-phenethyl-a-phenyl-4-piperidinemethanol alpha-Phenyl-1-(2-phenylethyl)-4-piperidinemethanol Glemanserin (USAN/INN) MDL 11,939phenyl[1-(2-phenylethyl)piperidin-4-yl]methanol phenyl-[1-(2-phenylethyl)piperidin-4-yl]methanol (1-phenethylpiperidin-4-yl)(phenyl)methanol 4-Piperidinemethanol,a-phenyl-1-(2-phenylethyl)- AN-24938 D04320 HMS3266L14 MDL-11939 SR-01000597432 107703-78-6 AC1Q771C BRD-A62057054-001-01-5 FT-0703731 LS-172057 PDSP2_001558 (+-)-1-Phenethyl-alpha-phenyl-4-piperidinemethanol 4-Piperidinemethanol, alpha-phenyl-1-(2-phenylethyl)- alpha-phenyl-[1-(2-phenylethyl )]-4-piperidinemethanol CHEMBL18972 Glemanserin [USAN:INN] Mdl 11939 RT-013670 [ Show all ]
Inchi Key	AXNGJCOYCMDPQG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H25NO/c22-20(18-9-5-2-6-10-18)19-12-15-21(16-13-19)14-11-17-7-3-1-4-8-17/h1-10,19-20,22H,11-16H2
PubChem CID	71781
ChEMBL	CHEMBL18972
IUPHAR	186
BindingDB	50004327
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16878	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
16879	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
16880	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
16885	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
16875	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
16884	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
16874	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
16887	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
16873	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
16883	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
16888	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
16882	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
16877	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
16889	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
16886	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
16881	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
16876	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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