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| Name | 5-hydroxytryptamine receptor 2A |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Htr2a |
| Synonym | serotonin 5HT-2 receptor 5Ht-2 'D' receptor 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 5-HT2A receptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 471 |
| Amino acid sequence | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYKSSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV |
| UniProt | P14842 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL322 |
| IUPHAR | 6 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 555478 |  Eticlopride | C17H25ClN2O3 | 340.848 | 4 / 2 | 3.1 | Yes |
| 258 |  CHEMBL109589 | C20H27NO | 297.442 | 2 / 1 | 5.1 | No |
| 260 |  CHEMBL122047 | C25H30ClFN4O2 | 472.989 | 4 / 0 | 4.5 | Yes |
| 290 |  CHEMBL1783352 | C24H26N6 | 398.514 | 5 / 1 | 3.5 | Yes |
| 547904 |  CHEMBL3883388 | C27H27Cl2FN4O3 | 545.436 | 7 / 0 | 6.0 | No |
| 743 |  CHEMBL367875 | C21H27N3OS | 369.527 | 4 / 0 | 3.4 | Yes |
| 781 |  4-(4-Fluorobenzoyl)piperidine | C12H14FNO | 207.248 | 3 / 1 | 1.7 | Yes |
| 941 |  CHEMBL233404 | C24H26N2O | 358.485 | 2 / 1 | 4.9 | Yes |
| 962 |  CHEMBL1917358 | C24H35N3O2S | 429.623 | 5 / 0 | 4.9 | Yes |
| 1385 |  CHEMBL489618 | C21H26FNO3 | 359.441 | 5 / 1 | 3.4 | Yes |
| 1475 |  4365 CT | C14H20N2O | 232.327 | 2 / 1 | 2.7 | Yes |
| 1490 |  CHEMBL413777 | C23H31NO2 | 353.506 | 3 / 1 | 5.7 | No |
| 1809 |  CHEMBL180319 | C15H17N3S2 | 303.442 | 4 / 0 | 3.0 | Yes |
| 521504 |  CHEMBL3741516 | C27H30FN3O2 | 447.554 | 5 / 0 | 4.7 | Yes |
| 555489 |  AC1N0YGA | C3H7NO4S | 153.152 | 5 / 2 | -4.7 | Yes |
| 555492 |  FK 1052 | C18H19N3O | 293.37 | 2 / 1 | 3.2 | Yes |
| 555495 |  2-Phenylcyclopropanamine | C9H11N | 133.194 | 1 / 1 | 1.5 | Yes |
| 3653 |  CHEMBL269396 | C21H22ClN | 323.864 | 1 / 0 | 6.1 | No |
| 3723 |  CHEMBL160354 | C30H38N2O6 | 522.642 | 7 / 2 | N/A | No |
| 3751 |  CHEMBL1173017 | C29H39N5 | 457.666 | 5 / 0 | 5.2 | No |
| 3764 |  CHEMBL566890 | C22H26ClN7O2 | 455.947 | 5 / 0 | 3.0 | Yes |
| 521560 |  CHEMBL3764080 | C20H24N4O3 | 368.437 | 6 / 1 | 1.3 | Yes |
| 4153 |  CHEMBL282255 | C26H26ClN3OS | 464.024 | 4 / 0 | 5.4 | No |
| 4155 |  CHEMBL21150 | C26H26ClN3OS | 464.024 | 4 / 0 | 5.4 | No |
| 4410 |  CHEMBL295689 | C13H16N4O | 244.298 | 5 / 0 | 1.2 | Yes |
| 4464 |  CHEMBL211301 | C13H19NO3 | 237.299 | 4 / 1 | 1.3 | Yes |
| 4465 |  CHEMBL379780 | C13H19NO3 | 237.299 | 4 / 1 | 1.3 | Yes |
| 4466 |  CHEMBL211309 | C13H19NO3 | 237.299 | 4 / 1 | 1.3 | Yes |
| 521577 |  CHEMBL3765273 | C19H23ClN4O | 358.87 | 4 / 1 | 2.7 | Yes |
| 547945 |  CHEMBL3883429 | C22H23Cl2N5O2 | 460.359 | 6 / 0 | 3.9 | Yes |
| 4616 |  CHEMBL95112 | C23H27FN2O2S | 414.539 | 6 / 0 | 3.4 | Yes |
| 4948 |  CHEMBL3233865 | C30H32N2O4 | 484.596 | 6 / 0 | 5.6 | No |
| 5007 |  CHEMBL130585 | C21H23N3O3 | 365.433 | 4 / 0 | 3.8 | Yes |
| 5316 |  CHEMBL2260621 | C17H17NO3S | 315.387 | 5 / 1 | 3.5 | Yes |
| 5452 |  CHEMBL175226 | C19H24ClN3OS | 377.931 | 4 / 0 | 2.8 | Yes |
| 5715 |  CHEMBL517962 | C19H22N4OS | 354.472 | 6 / 0 | 3.9 | Yes |
| 5719 |  CHEMBL152289 | C14H19N | 201.313 | 1 / 0 | 3.1 | Yes |
| 5770 |  paroxetine | C19H20FNO3 | 329.371 | 5 / 1 | 3.5 | Yes |
| 6277 |  CHEMBL76237 | C19H22N2O3S | 358.456 | 4 / 0 | 3.5 | Yes |
| 6867 |  CHEMBL13632 | C17H17BrClNO | 366.683 | 2 / 1 | 4.7 | Yes |
| 7070 |  CHEMBL109673 | C22H24FNO2S | 385.497 | 5 / 0 | 4.1 | Yes |
| 7243 |  CHEMBL426813 | C21H24ClN3O3 | 401.891 | 5 / 0 | 2.6 | Yes |
| 7313 |  CHEMBL543613 | C22H24ClFN2O2S | 434.954 | 6 / 1 | N/A | N/A |
| 7376 |  CHEMBL75670 | C24H27N5OS2 | 465.634 | 7 / 0 | 5.2 | No |
| 442007 |  CHEMBL3215842 | C28H29Cl2N7O | 550.488 | 7 / 2 | N/A | No |
| 7685 |  CHEMBL42061 | C17H18N4O2 | 310.357 | 6 / 0 | 2.0 | Yes |
| 7690 |  CID 44581146 | C26H30N4O2 | 430.552 | 4 / 2 | 3.5 | Yes |
| 7809 |  CHEMBL2387242 | C31H31FN2O4 | 514.597 | 7 / 0 | 6.0 | No |
| 8025 |  CHEMBL105152 | C19H25NO | 283.415 | 2 / 1 | 4.4 | Yes |
| 8115 |  CHEMBL317333 | C26H24FN5 | 425.511 | 5 / 0 | 4.0 | Yes |
| 555512 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 8291 |  CHEMBL58283 | C25H33F2N5O | 457.57 | 7 / 1 | 4.8 | Yes |
| 8628 |  CHEMBL1836054 | C20H24ClN3O3 | 389.88 | 5 / 2 | 2.9 | Yes |
| 8792 |  CHEMBL262794 | C19H19N3O2S | 353.44 | 5 / 0 | 2.4 | Yes |
| 8857 |  CHEMBL394664 | C14H19NO3 | 249.31 | 4 / 2 | 0.8 | Yes |
| 8878 |  CHEMBL136684 | C19H20N4O2 | 336.395 | 6 / 1 | 3.1 | Yes |
| 8897 |  CHEMBL1949969 | C23H27ClN4O2S | 459.005 | 6 / 1 | 4.1 | Yes |
| 9222 |  CHEMBL232997 | C15H19NO4 | 277.32 | 5 / 2 | -1.1 | Yes |
| 9227 |  CHEMBL234641 | C23H23ClN2O | 378.9 | 2 / 1 | 5.2 | No |
| 547990 |  CHEMBL3883495 | C23H23Cl2FN4O2 | 477.361 | 6 / 0 | 4.8 | Yes |
| 9673 |  BDBM50359431 | C24H27N3O3 | 405.498 | 4 / 2 | 2.8 | Yes |
| 10066 |  CHEMBL2299241 | C25H27ClN6S | 479.043 | 7 / 1 | 5.8 | No |
| 10089 |  CHEMBL585105 | C22H27N7O2 | 421.505 | 5 / 0 | 2.4 | Yes |
| 521733 |  CHEMBL3740636 | C26H30FN3O3 | 451.542 | 6 / 0 | 4.3 | Yes |
| 10292 |  CHEMBL234827 | C22H23N3O | 345.446 | 3 / 1 | 3.5 | Yes |
| 521737 |  CHEMBL3741553 | C24H28FN3O3S | 457.564 | 7 / 0 | 4.0 | Yes |
| 10362 |  CHEMBL6426 | C11H11BrN2 | 251.127 | 1 / 2 | 2.2 | Yes |
| 10858 |  CHEMBL358474 | C19H22FNO | 299.389 | 3 / 1 | 4.2 | Yes |
| 10965 |  CHEMBL2113277 | C27H33FN2O2S | 468.631 | 6 / 0 | 6.5 | No |
| 553303 |  tryptamine | C10H12N2 | 160.22 | 1 / 2 | 1.6 | Yes |
| 11081 |  60547-97-9 | C14H19N5O2 | 289.339 | 7 / 2 | 1.0 | Yes |
| 11177 |  ISOCLOZAPINE | C18H19ClN4 | 326.828 | 3 / 1 | 3.1 | Yes |
| 11678 |  CHEMBL224935 | C27H34N4O | 430.596 | 4 / 1 | 4.2 | Yes |
| 11700 |  Propranolol, L- | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 555525 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 12058 |  BDBM50054398 | C19H26N4O3 | 358.442 | 5 / 1 | 1.8 | Yes |
| 12125 |  CHEMBL476260 | C23H25ClN4O3 | 440.928 | 5 / 1 | 2.5 | Yes |
| 12461 |  CHEMBL338696 | C22H25FN2O | 352.453 | 3 / 1 | 3.6 | Yes |
| 553313 |  1-Isopropyltryptamine | C13H18N2 | 202.301 | 1 / 1 | 2.0 | Yes |
| 12469 |  BDBM50359428 | C19H26N2O3S | 362.488 | 5 / 2 | 3.4 | Yes |
| 13542 |  CHEMBL41462 | C22H21N3 | 327.431 | 3 / 0 | 5.0 | Yes |
| 13646 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 555537 |  BDBM86280 | C17H18BrNO2 | 348.24 | 3 / 3 | 3.2 | Yes |
| 13760 |  CHEMBL43486 | C14H18N4O | 258.325 | 5 / 0 | 1.6 | Yes |
| 14010 |  CHEMBL102268 | C20H27NO2 | 313.441 | 3 / 1 | 4.4 | Yes |
| 14098 |  CHEMBL226758 | C20H25N3O5 | 387.436 | 6 / 2 | 1.0 | Yes |
| 14120 |  CHEMBL2260619 | C17H17NO2S | 299.388 | 4 / 0 | 4.6 | Yes |
| 442199 |  CID 118724634 | C22H31ClN6O3 | 462.979 | 6 / 1 | N/A | N/A |
| 14505 |  CHEMBL119323 | C13H16BrNO2 | 298.18 | 3 / 1 | 2.0 | Yes |
| 14507 |  CHEMBL331864 | C13H16BrNO2 | 298.18 | 3 / 1 | 2.0 | Yes |
| 521890 |  CHEMBL3741933 | C23H32FN3O2 | 401.526 | 5 / 0 | 4.1 | Yes |
| 15116 |  CHEMBL153735 | C18H19ClFNO | 319.804 | 3 / 1 | 4.5 | Yes |
| 15236 |  CHEMBL342388 | C14H16N2O | 228.295 | 2 / 1 | 2.6 | Yes |
| 15452 |  CHEMBL87717 | C23H24FNO2 | 365.448 | 4 / 0 | 4.0 | Yes |
| 15458 |  CHEMBL158729 | C27H32N2O6 | 480.561 | 7 / 3 | N/A | N/A |
| 15643 |  CHEMBL1836104 | C23H28N2O2 | 364.489 | 3 / 1 | 4.1 | Yes |
| 15795 |  CHEMBL3216071 | C23H25Cl2N5O | 458.387 | 5 / 2 | N/A | N/A |
| 15845 |  CHEMBL565707 | C25H31N3O4 | 437.54 | 6 / 1 | 4.5 | Yes |
| 15931 |  CHEMBL434079 | C31H42N2O6 | 538.685 | 7 / 2 | N/A | No |
| 16037 |  ISOLOXAPINE | C18H18ClN3O | 327.812 | 3 / 0 | 3.1 | Yes |
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