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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4365 CT
Molecular formula	C14H20N2O
IUPAC name	2-(5-methoxy-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine
Molecular weight	232.327
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	2.7
Synonyms	67292-68-6 INDOLE, 3-(2-(DIMETHYLAMINO)ETHYL)-5-METHOXY-2-METHYL- ZINC1996368 BDBM50085972 PDSP1_001416 [2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-ammonium 4-22-00-05694 (Beilstein Handbook Reference) CHEMBL7143 UNII-XZ2CCP18I2 5-methoxy-2-methyl-n,n-dimethyltryptamine AC1L2MB5 LS-82938 [2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-amine 2,N,N-Trimethyl-5-methoxy-1H-indole-3-ethanamine BRN 0179917 PDSP2_001400 DTXSID10217627 XZ2CCP18I2 AC1Q56LA Methyl-2-methoxy-5-N-dimethyltryptamine [2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-amine (C2H2O) 2-(5-methoxy-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine SCHEMBL5766124 5-Methoxy-2,N,N-trimethyltryptamine [ Show all ]
Inchi Key	ACEHBQPPDDGCGZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H20N2O/c1-10-12(7-8-16(2)3)13-9-11(17-4)5-6-14(13)15-10/h5-6,9,15H,7-8H2,1-4H3
PubChem CID	49756
ChEMBL	CHEMBL7143
IUPHAR	N/A
BindingDB	50085972
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1476	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
1474	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
1469	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
1475	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
1472	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
1473	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
1471	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
1468	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
1470	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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