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| Name | 5-hydroxytryptamine receptor 7 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | HTR7 |
| Synonym | 5-HT-7 Serotonin receptor 7 5-HT-X 5-HT1Y 5-HT7 [ Show all ] |
| Disease | Sleep disorders Schizophrenia Major depressive disorder |
| Length | 479 |
| Amino acid sequence | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD |
| UniProt | P34969 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P34969 |
| 3D structure model | This predicted structure model is from GPCR-EXP P34969. |
| BioLiP | N/A |
| Therapeutic Target Database | T79062 |
| ChEMBL | CHEMBL3155 |
| IUPHAR | 12 |
| DrugBank | BE0000650, BE0004862 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 521456 |  CHEMBL3818128 | C19H23ClFN | 319.848 | 2 / 1 | N/A | N/A |
| 959 |  CHEMBL1917358 | C24H35N3O2S | 429.623 | 5 / 0 | 4.9 | Yes |
| 983 |  CHEMBL175781 | C22H23Cl2N3O | 416.346 | 3 / 0 | 5.0 | Yes |
| 1030 |  CHEMBL2205816 | C18H20N2O | 280.371 | 3 / 1 | 1.8 | Yes |
| 1441 |  CHEMBL84660 | C24H30N2OS | 394.577 | 3 / 0 | 4.5 | Yes |
| 1470 |  4365 CT | C14H20N2O | 232.327 | 2 / 1 | 2.7 | Yes |
| 441743 |  CHEMBL329566 | C20H23NO | 293.41 | 2 / 0 | 3.6 | Yes |
| 1921 |  CHEMBL371352 | C20H23NO | 293.41 | 2 / 0 | 3.6 | Yes |
| 2262 |  1-(cyclohexylmethyl)pyrrolidine | C11H21N | 167.296 | 1 / 0 | 3.1 | Yes |
| 2331 |  CHEMBL249797 | C24H28N4O2S | 436.574 | 6 / 2 | 3.9 | Yes |
| 2918 |  CHEMBL446459 | C14H19F2N3O | 283.323 | 4 / 2 | 2.6 | Yes |
| 521528 |  CHEMBL3763534 | C22H27ClN2O | 370.921 | 2 / 1 | N/A | N/A |
| 521534 |  CHEMBL3818805 | C24H27ClN4O | 422.957 | 2 / 2 | 4.8 | Yes |
| 3132 |  AC1N0YGA | C3H7NO4S | 153.152 | 5 / 2 | -4.7 | Yes |
| 547932 |  CHEMBL3941102 | C28H31F3N4O2 | 512.577 | 8 / 1 | 3.9 | No |
| 3244 |  CHEMBL2442997 | C28H34N4O3 | 474.605 | 6 / 1 | 3.0 | Yes |
| 3341 |  CHEMBL316039 | C21H26N4O | 350.466 | 3 / 2 | 2.4 | Yes |
| 3406 |  CHEMBL1642882 | C18H19ClN4O2S | 390.886 | 5 / 3 | 3.4 | Yes |
| 3645 |  CHEMBL3235731 | C22H34N4O3 | 402.539 | 5 / 1 | 1.8 | Yes |
| 3692 |  CHEMBL2158025 | C29H29N3OS | 467.631 | 4 / 1 | 6.2 | No |
| 4068 |  CHEMBL3262426 | C27H32N2O | 400.566 | 3 / 1 | 6.0 | No |
| 4097 |  CHEMBL1173578 | C21H16ClN5O2S2 | 469.962 | 7 / 0 | 4.6 | Yes |
| 4128 |  CHEMBL1836792 | C24H24F4N2O | 432.463 | 6 / 1 | 4.8 | Yes |
| 4613 |  CHEMBL2159474 | C16H17Cl3N2O3S2 | 455.793 | 6 / 1 | 5.0 | Yes |
| 4792 |  CHEMBL601885 | C30H40N4O3S | 536.735 | 7 / 0 | 5.7 | No |
| 5244 |  SB-258719 | C18H30N2O2S | 338.51 | 4 / 0 | 3.5 | Yes |
| 5621 |  CHEMBL1836788 | C21H26N4O | 350.466 | 4 / 1 | 2.8 | Yes |
| 5681 |  AC1L1HUK | C29H28ClN3O4 | 518.01 | 4 / 2 | 5.2 | No |
| 5845 |  CHEMBL70889 | C28H32N4O2 | 456.59 | 3 / 2 | 3.4 | Yes |
| 5988 |  CHEMBL601457 | C27H33N3O2S | 463.64 | 5 / 0 | 5.1 | No |
| 521637 |  CHEMBL3758684 | C23H30ClN3O2 | 415.962 | 3 / 2 | 4.9 | Yes |
| 6274 |  CHEMBL76237 | C19H22N2O3S | 358.456 | 4 / 0 | 3.5 | Yes |
| 6409 |  CHEMBL260906 | C30H29F4N5O2 | 567.589 | 9 / 1 | 4.7 | No |
| 441952 |  CHEMBL3409037 | C30H48N4O2 | 496.74 | 4 / 0 | 4.9 | Yes |
| 6807 |  CHEMBL206305 | C24H31NO2S | 397.577 | 3 / 0 | 4.9 | Yes |
| 463729 |  CHEMBL3633757 | C26H24BrNO4 | 494.385 | 5 / 0 | 5.4 | No |
| 521652 |  CHEMBL3764136 | C24H31ClN2O | 398.975 | 2 / 1 | N/A | N/A |
| 536124 |  CHEMBL3899832 | C22H19N5O4 | 417.425 | 8 / 2 | 3.6 | Yes |
| 7173 |  CHEMBL2159481 | C24H24F2N2O3S | 458.524 | 7 / 1 | 4.6 | Yes |
| 7825 |  CHEMBL469668 | C20H29F3N2O2 | 386.459 | 7 / 1 | 3.9 | Yes |
| 547978 |  CHEMBL3983496 | C32H41N3O4 | 531.697 | 6 / 1 | 5.2 | No |
| 7927 |  CHEMBL3121412 | C31H30N2O4 | 494.591 | 5 / 2 | N/A | N/A |
| 7934 |  CHEMBL493402 | C22H31N3O4S | 433.567 | 7 / 1 | 3.3 | Yes |
| 555513 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 8386 |  CHEMBL2159476 | C16H19ClN2O3S2 | 386.909 | 6 / 1 | 3.8 | Yes |
| 521695 |  CHEMBL3754496 | C16H19FN2 | 258.34 | 2 / 1 | 2.9 | Yes |
| 8829 |  CHEMBL2159463 | C22H27FN2O3 | 386.467 | 5 / 1 | 3.9 | Yes |
| 8894 |  CHEMBL1949969 | C23H27ClN4O2S | 459.005 | 6 / 1 | 4.1 | Yes |
| 9542 |  GSK163090 | C25H29N5O | 415.541 | 4 / 1 | 3.4 | Yes |
| 442086 |  CHEMBL3326992 | C28H32ClN3O2 | 478.033 | 4 / 1 | 5.2 | No |
| 9879 |  AC-42 | C20H31NO | 301.474 | 2 / 0 | 5.2 | No |
| 10187 |  CHEMBL194206 | C23H30FN5O2 | 427.524 | 6 / 1 | 2.7 | Yes |
| 10310 |  CHEMBL3121417 | C31H33N3O4 | 511.622 | 6 / 2 | N/A | No |
| 548006 |  CHEMBL3894679 | C28H30F4N4O2 | 530.568 | 9 / 1 | 4.3 | No |
| 10732 |  CHEMBL3287723 | C25H32O7 | 444.524 | 7 / 2 | 5.7 | No |
| 10907 |  CHEMBL28056 | C25H22N2 | 350.465 | 2 / 0 | 5.2 | No |
| 548013 |  CHEMBL3984812 | C25H27ClN2O2 | 422.953 | 4 / 0 | 5.5 | No |
| 11051 |  tryptamine | C10H12N2 | 160.22 | 1 / 2 | 1.6 | Yes |
| 521751 |  CHEMBL3746079 | C24H33FN2O3S | 448.597 | 6 / 0 | 5.1 | No |
| 11478 |  CHEMBL69040 | C25H30N4O3 | 434.54 | 5 / 1 | 4.1 | Yes |
| 11583 |  CHEMBL566639 | C18H20N4 | 292.386 | 3 / 2 | 2.9 | Yes |
| 11651 |  CHEMBL1782812 | C20H28N2O2S | 360.516 | 5 / 1 | 2.7 | Yes |
| 521775 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 11975 |  CHEMBL305526 | C27H31N3O | 413.565 | 2 / 1 | 4.3 | Yes |
| 12290 |  CHEMBL512609 | C21H18O12 | 462.363 | 12 / 7 | 0.8 | No |
| 12640 |  CHEMBL2312639 | C23H26Cl2N4O2S | 493.447 | 6 / 1 | 5.0 | Yes |
| 12842 |  CHEMBL495250 | C22H28F3N3O3S | 471.539 | 9 / 1 | 4.2 | Yes |
| 13472 |  CHEMBL599000 | C15H20N4 | 256.353 | 4 / 0 | 1.9 | Yes |
| 13668 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 13876 |  CHEMBL1836787 | C24H29Cl2N3O | 446.416 | 3 / 1 | 5.5 | No |
| 442201 |  CID 118724634 | C22H31ClN6O3 | 462.979 | 6 / 1 | N/A | N/A |
| 14124 |  CHEMBL409358 | C29H30FN5O2 | 499.59 | 6 / 1 | 3.8 | Yes |
| 14251 |  180083-23-2 | C32H32N4O3 | 520.633 | 6 / 0 | 5.6 | No |
| 14992 |  CHEMBL1917339 | C21H29N3O2S | 387.542 | 5 / 1 | 2.4 | Yes |
| 15084 |  CHEMBL1917354 | C26H34N4O3S | 482.643 | 7 / 0 | 4.0 | Yes |
| 521902 |  CHEMBL3765597 | C22H28ClN3O | 385.936 | 3 / 1 | N/A | N/A |
| 15318 |  CHEMBL489028 | C26H29N3O | 399.538 | 3 / 0 | 4.5 | Yes |
| 521911 |  CHEMBL3819567 | C24H28N4OS | 420.575 | 5 / 1 | 4.8 | Yes |
| 15480 |  CHEMBL2205829 | C19H19NO3 | 309.365 | 4 / 1 | 2.2 | Yes |
| 15996 |  CHEMBL1836784 | C24H30FN3O | 395.522 | 4 / 1 | 4.3 | Yes |
| 16022 |  CHEMBL506875 | C27H31N3O | 413.565 | 3 / 0 | 4.9 | Yes |
| 442282 |  CHEMBL3321789 | C22H25ClFNO2 | 389.895 | 4 / 1 | 4.8 | Yes |
| 442290 |  CHEMBL3343673 | C18H17N3O2 | 307.353 | 2 / 2 | 2.2 | Yes |
| 442291 |  CHEMBL3343672 | C18H17N3O2 | 307.353 | 2 / 2 | 2.2 | Yes |
| 557735 |  BDBM233049 | C18H25ClN4 | 332.876 | 3 / 0 | 3.3 | Yes |
| 16420 |  CHEMBL1917359 | C24H35N3O2S | 429.623 | 5 / 0 | 4.9 | Yes |
| 16659 |  CHEMBL2401934 | C26H27ClN2O4 | 466.962 | 6 / 1 | N/A | N/A |
| 442316 |  CHEMBL3401470 | C22H28N4OS | 396.553 | 5 / 1 | 3.7 | Yes |
| 548085 |  CHEMBL3952251 | C20H23Cl2NO | 364.31 | 2 / 1 | N/A | N/A |
| 548090 |  CHEMBL3910730 | C31H32FN5O | 509.629 | 6 / 1 | 4.8 | No |
| 19660 |  CHEMBL355202 | C25H25N3O | 383.495 | 3 / 1 | 4.5 | Yes |
| 19802 |  CHEMBL3233671 | C27H36ClFN4O2 | 503.059 | 5 / 1 | N/A | No |
| 20198 |  imipramine | C19H24N2 | 280.415 | 2 / 0 | 4.8 | Yes |
| 442469 |  CHEMBL3331258 | C22H27N3OS | 381.538 | 4 / 0 | 4.6 | Yes |
| 20753 |  CHEMBL3290000 | C20H24FN3O3S2 | 437.548 | 8 / 1 | 3.8 | Yes |
| 20938 |  SB-258585 | C18H22IN3O3S | 487.356 | 6 / 1 | 3.0 | Yes |
| 20996 |  CHEMBL433134 | C19H26BrN3 | 376.342 | 2 / 0 | 3.6 | Yes |
| 21138 |  CHEMBL152595 | C23H32N2O2S | 400.581 | 4 / 0 | 4.9 | Yes |
| 21141 |  SCHEMBL3825498 | C23H32N2O2S | 400.581 | 4 / 0 | 4.9 | Yes |
| 21157 |  CHEMBL114012 | C23H32N2O2S | 400.581 | 4 / 0 | 4.9 | Yes |
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