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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL469668
Molecular formula	C20H29F3N2O2
IUPAC name	1-[(1S)-2-(4-methylpiperazin-1-yl)-1-[3-(trifluoromethoxy)phenyl]ethyl]cyclohexan-1-ol
Molecular weight	386.459
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.9
Synonyms	BDBM50242927 SCHEMBL4625301 (-)-1-{(1S)-2-(4-Methylpiperazin-1-yl)-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrocholoride CHEMBL599411
Inchi Key	AKRIZMRTOCYSRB-GOSISDBHSA-N
Inchi ID	InChI=1S/C20H29F3N2O2/c1-24-10-12-25(13-11-24)15-18(19(26)8-3-2-4-9-19)16-6-5-7-17(14-16)27-20(21,22)23/h5-7,14,18,26H,2-4,8-13,15H2,1H3/t18-/m1/s1
PubChem CID	11574574
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50242927
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7827	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
7822	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
7826	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
7824	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
7823	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
7825	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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