You can:
| Name | 5-hydroxytryptamine receptor 1D |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | HTR1D |
| Synonym | Serotonin 1D alpha receptor serotonin receptor 1D HTRL Htr1db 5-HT-1D [ Show all ] |
| Disease | Acute migraine Epilepsy Migraine headaches Mood disorder Migraine [ Show all ] |
| Length | 377 |
| Amino acid sequence | MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS |
| UniProt | P28221 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P28221 |
| 3D structure model | This predicted structure model is from GPCR-EXP P28221. |
| BioLiP | N/A |
| Therapeutic Target Database | T11072 |
| ChEMBL | CHEMBL1983 |
| IUPHAR | 3 |
| DrugBank | BE0000659 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 174 |  CHEMBL2111779 | C24H25N3O2 | 387.483 | 4 / 1 | 3.8 | Yes |
| 176 |  CHEMBL119800 | C24H25N3O2 | 387.483 | 4 / 1 | 3.8 | Yes |
| 624 |  CHEMBL306197 | C25H32N2O | 376.544 | 2 / 1 | 6.0 | No |
| 553252 |  7-Hydroxy Risperidone | C23H27FN4O3 | 426.492 | 7 / 1 | 1.7 | Yes |
| 1329 |  CHEMBL109839 | C21H34N2O | 330.516 | 2 / 2 | 5.6 | No |
| 1382 |  CHEMBL352181 | C26H30N4S | 430.614 | 3 / 2 | 4.8 | Yes |
| 1417 |  CHEMBL119145 | C22H24N4O2 | 376.46 | 3 / 3 | 2.4 | Yes |
| 1474 |  4365 CT | C14H20N2O | 232.327 | 2 / 1 | 2.7 | Yes |
| 1698 |  CHEMBL470849 | C25H28N4O2 | 416.525 | 5 / 1 | 3.8 | Yes |
| 1753 |  CHEMBL89448 | C16H24N4O2 | 304.394 | 4 / 3 | 1.4 | Yes |
| 2158 |  CHEMBL81703 | C25H25FN2O2S | 436.545 | 5 / 1 | 3.9 | Yes |
| 2181 |  CHEMBL458002 | C29H28ClN5O2 | 514.026 | 5 / 2 | 4.3 | No |
| 2256 |  1-(cyclohexylmethyl)pyrrolidine | C11H21N | 167.296 | 1 / 0 | 3.1 | Yes |
| 2914 |  CHEMBL446459 | C14H19F2N3O | 283.323 | 4 / 2 | 2.6 | Yes |
| 3141 |  AC1N0YGA | C3H7NO4S | 153.152 | 5 / 2 | -4.7 | Yes |
| 3403 |  CHEMBL1642882 | C18H19ClN4O2S | 390.886 | 5 / 3 | 3.4 | Yes |
| 3985 |  CHEMBL109360 | C17H24N2O2 | 288.391 | 3 / 1 | 2.7 | Yes |
| 4302 |  Butanedioic acid, compd. with 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (1:1) | C18H22N2O5 | 346.383 | 6 / 4 | N/A | N/A |
| 4560 |  CHEMBL495161 | C25H30N4O2 | 418.541 | 5 / 1 | 3.1 | Yes |
| 5060 |  BDBM50068818 | C32H39N5O6 | 589.693 | 8 / 2 | 2.9 | No |
| 5239 |  CHEMBL420867 | C22H26N4O | 362.477 | 2 / 2 | 2.5 | Yes |
| 5247 |  SB-258719 | C18H30N2O2S | 338.51 | 4 / 0 | 3.5 | Yes |
| 6141 |  CHEMBL144128 | C28H38N6O2 | 490.652 | 6 / 4 | 2.3 | Yes |
| 6279 |  CHEMBL76237 | C19H22N2O3S | 358.456 | 4 / 0 | 3.5 | Yes |
| 463737 |  CHEMBL3633757 | C26H24BrNO4 | 494.385 | 5 / 0 | 5.4 | No |
| 536147 |  CHEMBL3899832 | C22H19N5O4 | 417.425 | 8 / 2 | 3.6 | Yes |
| 7822 |  CHEMBL469668 | C20H29F3N2O2 | 386.459 | 7 / 1 | 3.9 | Yes |
| 8204 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 8249 |  CHEMBL2260924 | C15H20Br2N2O5 | 468.142 | 7 / 2 | N/A | N/A |
| 521683 |  CHEMBL3754496 | C16H19FN2 | 258.34 | 2 / 1 | 2.9 | Yes |
| 8805 |  CHEMBL198488 | C31H33N7O | 519.653 | 6 / 0 | 4.7 | No |
| 9003 |  naratriptan | C17H25N3O2S | 335.466 | 4 / 2 | 2.0 | Yes |
| 9386 |  CHEMBL356315 | C27H34N6O | 458.61 | 5 / 3 | 3.3 | Yes |
| 9388 |  CHEMBL143947 | C27H34N6O | 458.61 | 5 / 3 | 3.3 | Yes |
| 9545 |  GSK163090 | C25H29N5O | 415.541 | 4 / 1 | 3.4 | Yes |
| 9700 |  CHEMBL309162 | C12H16N2O | 204.273 | 2 / 2 | 1.2 | Yes |
| 10178 |  CHEMBL194206 | C23H30FN5O2 | 427.524 | 6 / 1 | 2.7 | Yes |
| 10261 |  CHEMBL164111 | C22H26N6O | 390.491 | 5 / 1 | 2.2 | Yes |
| 10441 |  SB 204070 hydrochloride | C19H27ClN2O4 | 382.885 | 6 / 1 | 3.5 | Yes |
| 10699 |  CHEMBL114303 | C28H36N6O | 472.637 | 5 / 2 | 3.5 | Yes |
| 10725 |  CHEMBL3287723 | C25H32O7 | 444.524 | 7 / 2 | 5.7 | No |
| 10970 |  CHEMBL143952 | C25H30N6O2S | 478.615 | 6 / 2 | 3.3 | Yes |
| 11011 |  CHEMBL458200 | C29H36N4O2 | 472.633 | 5 / 0 | 4.7 | Yes |
| 11062 |  tryptamine | C10H12N2 | 160.22 | 1 / 2 | 1.6 | Yes |
| 11232 |  CHEMBL1241912 | C28H30N6O2 | 482.588 | 6 / 1 | 3.4 | Yes |
| 11734 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 12121 |  CHEMBL331037 | C27H37N5O4S | 527.684 | 7 / 3 | 2.4 | No |
| 12524 |  CHEMBL333341 | C27H34N6 | 442.611 | 4 / 1 | 4.1 | Yes |
| 12606 |  CHEMBL162012 | C27H32N4O | 428.58 | 3 / 2 | 4.6 | Yes |
| 13026 |  CHEMBL79725 | C24H26FN3O2 | 407.489 | 4 / 2 | 3.0 | Yes |
| 13352 |  CHEMBL343105 | C17H24N2O | 272.392 | 2 / 0 | 2.4 | Yes |
| 13561 |  CHEMBL315757 | C20H24N4O | 336.439 | 4 / 3 | 4.4 | Yes |
| 13632 |  CHEMBL26998 | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 13655 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 13984 |  CHEMBL1289163 | C26H27FN4O | 430.527 | 5 / 0 | 4.2 | Yes |
| 14239 |  180083-23-2 | C32H32N4O3 | 520.633 | 6 / 0 | 5.6 | No |
| 15598 |  CHEMBL246598 | C28H33N3O3 | 459.59 | 5 / 0 | 4.8 | Yes |
| 16631 |  CHEMBL351036 | C26H29ClN4S | 465.056 | 3 / 2 | 5.4 | No |
| 16682 |  CHEMBL282229 | C30H32N4O4 | 512.61 | 7 / 0 | 5.2 | No |
| 16779 |  Pipamperone | C21H30FN3O2 | 375.488 | 5 / 1 | 2.0 | Yes |
| 17185 |  CHEMBL303021 | C18H25ClN2 | 304.862 | 1 / 1 | 5.2 | No |
| 17273 |  CHEMBL147546 | C29H37N7O | 499.663 | 5 / 2 | 3.6 | Yes |
| 17380 |  CHEMBL88152 | C17H22N4O | 298.39 | 5 / 2 | 2.7 | Yes |
| 17431 |  CHEMBL83617 | C25H26FN3O2 | 419.5 | 4 / 2 | 3.0 | Yes |
| 18507 |  SCHEMBL2881638 | C27H34N4O | 430.596 | 4 / 1 | 5.1 | No |
| 18650 |  CHEMBL345657 | C23H27N7 | 401.518 | 5 / 2 | 1.9 | Yes |
| 557845 |  CHEMBL75420 | C18H27N5O | 329.448 | 3 / 3 | 3.4 | Yes |
| 19072 |  CHEMBL282693 | C28H31N5O3 | 485.588 | 7 / 2 | 5.0 | Yes |
| 19113 |  CHEMBL162771 | C26H36N4O | 420.601 | 3 / 2 | 4.6 | Yes |
| 19551 |  CHEMBL106807 | C24H31ClN4O2 | 442.988 | 5 / 0 | 3.9 | Yes |
| 19668 |  CHEMBL355202 | C25H25N3O | 383.495 | 3 / 1 | 4.5 | Yes |
| 20093 |  CHEMBL1631541 | C26H31N5O | 429.568 | 4 / 1 | 3.8 | Yes |
| 20209 |  CHEMBL297660 | C17H24N2 | 256.393 | 1 / 1 | 3.6 | Yes |
| 20322 |  CHEMBL423212 | C24H30N6S | 434.606 | 5 / 1 | 3.7 | Yes |
| 557910 |  CHEMBL76552 | C18H27N5O | 329.448 | 3 / 3 | 3.7 | Yes |
| 20738 |  CHEMBL350153 | C28H36N4O2 | 460.622 | 4 / 1 | 4.3 | Yes |
| 20814 |  CHEMBL509314 | C51H60F2N6O2 | 827.078 | 6 / 4 | 11.0 | No |
| 20929 |  CHEMBL118243 | C26H31N5O3 | 461.566 | 4 / 3 | 2.7 | Yes |
| 21140 |  SCHEMBL3825498 | C23H32N2O2S | 400.581 | 4 / 0 | 4.9 | Yes |
| 21151 |  CHEMBL114012 | C23H32N2O2S | 400.581 | 4 / 0 | 4.9 | Yes |
| 21786 |  CHEMBL357034 | C15H22N2 | 230.355 | 1 / 2 | 3.2 | Yes |
| 22561 |  CHEMBL283036 | C19H19F3N4 | 360.384 | 6 / 1 | 3.6 | Yes |
| 23314 |  23869-98-9 | C16H24N2O2 | 276.38 | 3 / 3 | 2.5 | Yes |
| 23381 |  CHEMBL309872 | C25H26ClN3O2 | 435.952 | 3 / 2 | 3.5 | Yes |
| 23565 |  CHEMBL450852 | C44H44F2N6O2 | 726.873 | 6 / 4 | 7.2 | No |
| 23704 |  CHEMBL88207 | C18H23N3O | 297.402 | 4 / 2 | 3.8 | Yes |
| 23799 |  CHEMBL191619 | C23H25Cl2N3O | 430.373 | 4 / 0 | 5.2 | No |
| 24288 |  CHEMBL2181168 | C21H24IN3O | 461.347 | 4 / 0 | 5.1 | No |
| 24535 |  CHEMBL511279 | C26H28F2N4O2 | 466.533 | 7 / 0 | 4.5 | Yes |
| 24808 |  lysergol | C16H18N2O | 254.333 | 2 / 2 | 2.2 | Yes |
| 24814 |  Lysergole | C16H18N2O | 254.333 | 2 / 2 | 2.2 | Yes |
| 536620 |  2-Chloroadenosine | C10H12ClN5O4 | 301.687 | 8 / 4 | -0.1 | Yes |
| 26014 |  CHEMBL334092 | C20H31N5O3S | 421.56 | 7 / 0 | 1.6 | Yes |
| 26021 |  LISURIDE | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 26069 |  S-(-)-Lisuride | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 26083 |  AC1L1H1T | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 26286 |  CHEMBL600053 | C18H18FNO | 283.346 | 3 / 1 | 2.5 | Yes |
| 553393 |  Rauwolscine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26575 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26628 |  CHEBI:48565 | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
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