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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL119800
Molecular formula	C24H25N3O2
IUPAC name	3-[(E)-3-(dimethylamino)prop-1-enyl]-4-methoxy-N-(4-pyridin-4-ylphenyl)benzamide
Molecular weight	387.483
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.8
Synonyms	3-[(E)-3-(Dimethylamino)-1-propenyl]-4-methoxy-N-[4-(4-pyridinyl)phenyl]benzamide BDBM50060516 3-[(Z)-3-(Dimethylamino)-1-propenyl]-4-methoxy-N-[4-(4-pyridinyl)phenyl]benzamide 3-((E)-3-Dimethylamino-propenyl)-4-methoxy-N-(4-pyridin-4-yl-phenyl)-benzamide
Inchi Key	AAFLHUGZAQQWED-SNAWJCMRSA-N
Inchi ID	InChI=1S/C24H25N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h4-15,17H,16H2,1-3H3,(H,26,28)/b5-4+
PubChem CID	10643939
ChEMBL	CHEMBL119800
IUPHAR	N/A
BindingDB	50060516
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
175	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
177	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
176	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377

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