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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL81703
Molecular formula	C25H25FN2O2S
IUPAC name	1-[2-[4-(6-fluoro-1-benzothiophen-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3,4-dihydro-1H-isochromene-6-carboxamide
Molecular weight	436.545
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.9
Synonyms	BDBM50145336 1-{2-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Inchi Key	ADEBGCBREGNKQR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H25FN2O2S/c26-19-2-4-21-22(15-31-24(21)14-19)16-5-9-28(10-6-16)11-7-23-20-3-1-18(25(27)29)13-17(20)8-12-30-23/h1-5,13-15,23H,6-12H2,(H2,27,29)
PubChem CID	44460810
ChEMBL	CHEMBL81703
IUPHAR	N/A
BindingDB	50145336
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2159	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
2158	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
2160	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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