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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB-258719
Molecular formula	C18H30N2O2S
IUPAC name	N,3-dimethyl-N-[(2R)-4-(4-methylpiperidin-1-yl)butan-2-yl]benzenesulfonamide
Molecular weight	338.51
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.5
Synonyms	195199-95-2 BDBM50098550 N,3-dimethyl-N-[(2R)-4-(4-methylpiperidin-1-yl)butan-2-yl]benzenesulfonamide 3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide CHEMBL12264 GTPL281 SCHEMBL2471088 Benzenesulfonamide, N,3-dimethyl-N-(1-methyl-3-(4-methyl-1-piperidinyl)propyl)-, (R)- SB 258719 3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide (SB-258719) CS-0035396 SB-258719, >=98% (HPLC) (r)-3,n-dimethyl-n-[1-methyl-3-(4-methylpiperidin-1-yl)propyl]benzene sulfonamide AC1NSM3U HY-U00443 ZINC7275 3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide SB-258,719 4-Methyl-1-[(R)-3-methyl-4-(toluene-3-sulfonyl)-pentyl]-piperidine D0H9QG SB258719 [ Show all ]
Inchi Key	AGVNHDNTFYHZNL-QGZVFWFLSA-N
Inchi ID	InChI=1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3/t17-/m1/s1
PubChem CID	5312148
ChEMBL	CHEMBL12264
IUPHAR	281
BindingDB	50098550
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5249	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
5255	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
5247	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
5251	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
5250	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
5246	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
5248	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
5243	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
5254	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
555503	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
5253	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
5242	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
5244	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
5252	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
5245	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
5256	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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