You can:
| Name | 5-hydroxytryptamine receptor 7 |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Htr7 |
| Synonym | GPRFO 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 5-HTx 5-HT7 receptor 5-HT7 [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 448 |
| Amino acid sequence | MMDVNSSGRPDLYGHLRSLILPEVGRGLQDLSPDGGAHPVVSSWMPHLLSGFLEVTASPAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISLNGVVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNSDHCGKKGHDT |
| UniProt | P32305 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3223 |
| IUPHAR | 12 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 676 |  CHEMBL1644486 | C20H19ClN2 | 322.836 | 1 / 1 | 4.0 | Yes |
| 1194 |  CHEMBL12933 | C25H29N3O2S | 435.586 | 5 / 0 | 4.7 | Yes |
| 1468 |  4365 CT | C14H20N2O | 232.327 | 2 / 1 | 2.7 | Yes |
| 555485 |  Strychnine, Nb-oxide | C21H22N2O3 | 350.418 | 3 / 0 | 1.4 | Yes |
| 555496 |  BIMU-8 | C19H26N4O2 | 342.443 | 3 / 1 | 2.5 | Yes |
| 4455 |  CHEMBL369102 | C25H31N3O | 389.543 | 3 / 0 | 4.8 | Yes |
| 4906 |  CHEMBL1644281 | C20H20N2O | 304.393 | 2 / 2 | 3.0 | Yes |
| 5242 |  SB-258719 | C18H30N2O2S | 338.51 | 4 / 0 | 3.5 | Yes |
| 8137 |  CHEMBL390558 | C28H39N3O3 | 465.638 | 5 / 1 | 4.4 | Yes |
| 555514 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 8635 |  TCMDC-139048 | C21H22N2O | 318.42 | 2 / 1 | 3.7 | Yes |
| 9671 |  BDBM50359431 | C24H27N3O3 | 405.498 | 4 / 2 | 2.8 | Yes |
| 10904 |  CHEMBL28056 | C25H22N2 | 350.465 | 2 / 0 | 5.2 | No |
| 553304 |  tryptamine | C10H12N2 | 160.22 | 1 / 2 | 1.6 | Yes |
| 11076 |  CHEMBL187088 | C20H27N3O3S | 389.514 | 6 / 1 | 2.9 | Yes |
| 11237 |  CHEMBL3085301 | C25H24N2 | 352.481 | 2 / 0 | 5.0 | Yes |
| 11238 |  CHEMBL188855 | C25H24N2 | 352.481 | 2 / 0 | 5.0 | Yes |
| 11679 |  CHEMBL224935 | C27H34N4O | 430.596 | 4 / 1 | 4.2 | Yes |
| 555524 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 12468 |  BDBM50359428 | C19H26N2O3S | 362.488 | 5 / 2 | 3.4 | Yes |
| 13634 |  CHEMBL26998 | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 13682 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 16763 |  CHEMBL185988 | C27H27N3O3 | 441.531 | 5 / 0 | 3.8 | Yes |
| 17681 |  CHEMBL243955 | C28H40N4O | 448.655 | 4 / 1 | 4.6 | Yes |
| 18406 |  CHEMBL540821 | C18H20ClN3O | 329.828 | 2 / 3 | N/A | N/A |
| 19331 |  SCHEMBL2272659 | C17H19NO2 | 269.344 | 3 / 1 | 3.3 | Yes |
| 20019 |  CHEMBL229179 | C23H31ClN6O3 | 474.99 | 6 / 0 | 3.3 | Yes |
| 555561 |  imipramine | C19H24N2 | 280.415 | 2 / 0 | 4.8 | Yes |
| 21245 |  CHEMBL357800 | C26H36N2O2S | 440.646 | 4 / 0 | 6.5 | No |
| 21453 |  BDBM50359429 | C18H24N2O3S | 348.461 | 5 / 2 | 3.1 | Yes |
| 22320 |  CHEMBL363466 | C20H25NO2 | 311.425 | 3 / 0 | 4.2 | Yes |
| 555569 |  sulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 553389 |  LISURIDE | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 555581 |  S-(-)-Lisuride | C20H26N4O | 338.455 | 2 / 2 | 2.7 | Yes |
| 26391 |  CHEMBL243953 | C30H43N3O | 461.694 | 3 / 1 | 6.1 | No |
| 555590 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26693 |  CHEMBL157840 | C24H29N3O4 | 423.513 | 7 / 1 | 4.5 | Yes |
| 555591 |  7-OH-DPAT | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 27198 |  CHEMBL2203713 | C18H22N4S | 326.462 | 4 / 2 | 2.9 | Yes |
| 28304 |  CHEMBL244162 | C26H36N4O | 420.601 | 4 / 2 | 3.8 | Yes |
| 30219 |  LP-211 | C30H34N4O | 466.629 | 4 / 1 | 5.0 | Yes |
| 555596 |  morphine | C17H19NO3 | 285.343 | 4 / 2 | 0.8 | Yes |
| 31093 |  BDBM50359427 | C21H30N2O3S | 390.542 | 5 / 2 | 4.5 | Yes |
| 31803 |  CHEMBL362540 | C22H29N | 307.481 | 1 / 0 | 6.1 | No |
| 32012 |  SCHEMBL6530503 | C19H16ClFN2O2S | 390.857 | 4 / 0 | 3.4 | Yes |
| 555606 |  4-aminobutyric acid | C4H9NO2 | 103.121 | 3 / 2 | -3.2 | Yes |
| 33177 |  CHEMBL225441 | C27H37N3O3 | 451.611 | 5 / 1 | 4.0 | Yes |
| 467034 |  CHEMBL3590089 | C27H34N4O3 | 462.594 | 5 / 1 | 3.7 | Yes |
| 33450 |  CHEMBL389842 | C19H23N5O3 | 369.425 | 4 / 1 | 0.6 | Yes |
| 34244 |  SCHEMBL2272950 | C20H23NO2 | 309.409 | 3 / 1 | 4.2 | Yes |
| 34817 |  CHEMBL160817 | C23H27N3O3 | 393.487 | 6 / 1 | 4.6 | Yes |
| 35750 |  CHEMBL275495 | C21H26N2O | 322.452 | 2 / 0 | 4.3 | Yes |
| 36544 |  CHEMBL281357 | C17H17N | 235.33 | 1 / 0 | 3.0 | Yes |
| 36585 |  SCHEMBL6530751 | C21H21ClN2O4S | 432.919 | 5 / 0 | 3.3 | Yes |
| 36978 |  CHEMBL2431048 | C19H28ClN3O4 | 397.9 | 5 / 2 | N/A | N/A |
| 517506 |  CHEMBL141096 | C21H29NO2 | 327.468 | 2 / 2 | 4.2 | Yes |
| 38309 |  CHEMBL1644485 | C20H19ClN2 | 322.836 | 1 / 1 | 4.0 | Yes |
| 38923 |  CHEMBL283065 | C25H25NO2 | 371.48 | 3 / 0 | 5.1 | No |
| 39633 |  SCHEMBL2273377 | C16H14F3NO | 293.289 | 5 / 1 | 3.8 | Yes |
| 553446 |  Aripiprazole | C23H27Cl2N3O2 | 448.388 | 4 / 1 | 4.6 | Yes |
| 40981 |  CHEMBL1644487 | C20H18Cl2N2 | 357.278 | 1 / 1 | 4.6 | Yes |
| 41048 |  CHEMBL240729 | C48H66N4O4 | 763.08 | 8 / 0 | 10.9 | No |
| 41270 |  CHEMBL228940 | C21H27ClN6O3 | 446.936 | 5 / 1 | 2.6 | Yes |
| 42183 |  CHEMBL3640573 | C15H13Cl2NO | 294.175 | 2 / 1 | 4.6 | Yes |
| 42758 |  BDBM50359426 | C22H27N3O2 | 365.477 | 3 / 2 | 3.3 | Yes |
| 43038 |  CHEMBL1644279 | C20H19FN2 | 306.384 | 2 / 1 | 3.4 | Yes |
| 555653 |  naphazoline | C14H14N2 | 210.28 | 1 / 1 | 2.1 | Yes |
| 517540 |  CHEMBL137923 | C17H22O2 | 258.361 | 2 / 1 | 3.7 | Yes |
| 46629 |  CHEMBL222864 | C26H35N3O2 | 421.585 | 4 / 1 | 4.1 | Yes |
| 47775 |  CHEMBL243744 | C29H41N3O | 447.667 | 3 / 1 | 5.6 | No |
| 50013 |  SCHEMBL2273888 | C17H16N2O | 264.328 | 3 / 1 | 3.0 | Yes |
| 50060 |  CHEMBL229366 | C24H33ClN6O3 | 489.017 | 6 / 0 | 3.7 | Yes |
| 50569 |  UNII-87UKL3XE5X | C22H26N4O2 | 378.476 | 4 / 0 | 2.6 | Yes |
| 50578 |  CHEMBL285066 | C22H26N4O2 | 378.476 | 4 / 0 | 2.6 | Yes |
| 50950 |  CHEMBL222489 | C27H36N4O2 | 448.611 | 4 / 2 | 3.3 | Yes |
| 51796 |  SCHEMBL2277147 | C17H16N2O | 264.328 | 3 / 1 | 3.0 | Yes |
| 52725 |  CHEMBL1644488 | C21H21ClN2 | 336.863 | 1 / 0 | 4.4 | Yes |
| 52822 |  BDBM50359434 | C20H25N3O3 | 355.438 | 4 / 2 | 1.8 | Yes |
| 55106 |  CHEMBL27251 | C18H18N2 | 262.356 | 2 / 1 | 1.6 | Yes |
| 55111 |  CHEMBL281048 | C18H18N2 | 262.356 | 2 / 1 | 1.6 | Yes |
| 555684 |  fenfluramine | C12H16F3N | 231.262 | 4 / 1 | 3.4 | Yes |
| 56748 |  CHEMBL157362 | C23H27F3N2O2 | 420.476 | 7 / 1 | 5.3 | No |
| 555685 |  LY-278,584 maleate | C17H22N4O | 298.39 | 3 / 1 | 2.4 | Yes |
| 57509 |  CID 56850927 | C21H31ClN2O3S | 427.0 | 5 / 2 | N/A | N/A |
| 58218 |  CHEMBL390062 | C26H35N3O3 | 437.584 | 5 / 1 | 3.7 | Yes |
| 58485 |  CHEMBL273452 | C23H30N2O | 350.506 | 2 / 0 | 5.1 | No |
| 58665 |  CHEMBL389110 | C28H38N4O2 | 462.638 | 4 / 2 | 3.6 | Yes |
| 59233 |  SCHEMBL2278224 | C19H23NO2 | 297.398 | 3 / 1 | 4.1 | Yes |
| 517623 |  CHEMBL138043 | C17H20O3 | 272.344 | 3 / 2 | 3.2 | Yes |
| 555701 |  2-azaniumylacetate | C2H5NO2 | 75.067 | 2 / 1 | -2.8 | Yes |
| 60896 |  CHEMBL521687 | C25H35N3O4S2 | 505.692 | 7 / 1 | 3.7 | No |
| 62006 |  SCHEMBL2279377 | C17H19N | 237.346 | 1 / 1 | 3.7 | Yes |
| 62222 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 555720 |  MELPERONE | C16H22FNO | 263.356 | 3 / 0 | 3.3 | Yes |
| 64959 |  CHEMBL12868 | C20H26N2O2S | 358.5 | 4 / 0 | 4.0 | Yes |
| 66937 |  SCHEMBL2279423 | C18H21NO | 267.372 | 2 / 1 | 3.6 | Yes |
| 555738 |  Melatonin | C13H16N2O2 | 232.283 | 2 / 2 | 0.8 | Yes |
| 471259 |  CHEMBL3634821 | C29H28FN3O3 | 485.559 | 7 / 0 | 6.2 | No |
| 67471 |  CHEMBL1926745 | C21H29N3O3 | 371.481 | 4 / 1 | 2.0 | Yes |
| 67773 |  BDBM50359423 | C20H24N4O2 | 352.438 | 4 / 2 | 1.8 | Yes |
zhanglab
zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417