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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL363466
Molecular formula	C20H25NO2
IUPAC name	(2S)-5-(2,6-dimethoxyphenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine
Molecular weight	311.425
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.2
Synonyms	BDBM50150673 (3S)-3alpha-(Dimethylamino)-8-(2,6-dimethoxyphenyl)tetralin
Inchi Key	BFHVQDBLFZYJPG-HNNXBMFYSA-N
Inchi ID	InChI=1S/C20H25NO2/c1-21(2)15-11-12-16-14(13-15)7-5-8-17(16)20-18(22-3)9-6-10-19(20)23-4/h5-10,15H,11-13H2,1-4H3/t15-/m0/s1
PubChem CID	10064052
ChEMBL	CHEMBL363466
IUPHAR	N/A
BindingDB	50150673
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22319	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
22323	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
22325	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
22324	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
22322	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
22320	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
22321	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
22326	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
22327	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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