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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL389110
Molecular formula	C28H38N4O2
IUPAC name	6-[4-(2-acetamidophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Molecular weight	462.638
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.6
Synonyms	6-[4-(2-acetamidophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide BDBM21387 Piperazinehexanamide derivative, 25
Inchi Key	DFLMNRNLACOXKM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H38N4O2/c1-22(33)29-26-13-6-7-15-27(26)32-20-18-31(19-21-32)17-8-2-3-16-28(34)30-25-14-9-11-23-10-4-5-12-24(23)25/h4-7,10,12-13,15,25H,2-3,8-9,11,14,16-21H2,1H3,(H,29,33)(H,30,34)
PubChem CID	24768522
ChEMBL	CHEMBL389110
IUPHAR	N/A
BindingDB	21387
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
58666	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
58667	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
58665	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
58664	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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