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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL285066
Molecular formula	C22H26N4O2
IUPAC name	2-[(4-naphthalen-1-ylpiperazin-1-yl)methyl]-6,7,8,8a-tetrahydro-3H-pyrrolo[1,2-a]pyrazine-1,4-dione
Molecular weight	378.476
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.6
Synonyms	CSP-2503 2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione BDBM50126475
Inchi Key	CTZWGZSINBFHFD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26N4O2/c27-21-15-25(22(28)20-9-4-10-26(20)21)16-23-11-13-24(14-12-23)19-8-3-6-17-5-1-2-7-18(17)19/h1-3,5-8,20H,4,9-16H2
PubChem CID	10317515
ChEMBL	CHEMBL285066
IUPHAR	N/A
BindingDB	50126475
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
50576	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
50579	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
50580	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
50578	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
50577	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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