You can:
| Name | 5-hydroxytryptamine receptor 4 |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Htr4 |
| Synonym | 5-HT-4 5-HT4 5-HT4 receptor 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled serotonin receptor 4 |
| Disease | N/A for non-human GPCRs |
| Length | 406 |
| Amino acid sequence | MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSNSTFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS |
| UniProt | Q62758 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4317 |
| IUPHAR | 9 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 3301 |  CHEMBL94784 | C17H23ClN4O4S | 414.905 | 7 / 2 | 1.9 | Yes |
| 3666 |  CHEMBL3221571 | C18H26N4S | 330.494 | 3 / 2 | 3.4 | Yes |
| 553262 |  BIMU-8 | C19H26N4O2 | 342.443 | 3 / 1 | 2.5 | Yes |
| 4338 |  CHEMBL59834 | C19H26N4O2 | 342.443 | 3 / 1 | 2.5 | Yes |
| 5020 |  UNII-QPE81T4KH0 | C23H32FN3O4 | 433.524 | 6 / 2 | 2.5 | Yes |
| 5829 |  CHEMBL293070 | C26H34N4O | 418.585 | 3 / 1 | 5.1 | No |
| 6518 |  CHEMBL3126108 | C18H24ClFN2O4 | 386.848 | 7 / 1 | 2.9 | Yes |
| 6758 |  CHEMBL19039 | C17H20ClN3O2 | 333.816 | 4 / 1 | 3.5 | Yes |
| 6820 |  CHEMBL18769 | C14H17ClN4O | 292.767 | 3 / 2 | 2.0 | Yes |
| 6876 |  CHEMBL57948 | C19H28N4O | 328.46 | 3 / 1 | 3.1 | Yes |
| 6912 |  CHEMBL324057 | C20H28N4O2 | 356.47 | 3 / 1 | 2.9 | Yes |
| 553279 |  RS57639 | C25H31ClN2O5 | 474.982 | 7 / 1 | 4.5 | Yes |
| 7391 |  CHEMBL298920 | C16H24N2O3 | 292.379 | 4 / 1 | 3.3 | Yes |
| 555511 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 9670 |  BDBM50359431 | C24H27N3O3 | 405.498 | 4 / 2 | 2.8 | Yes |
| 10446 |  SB 204070 hydrochloride | C19H27ClN2O4 | 382.885 | 6 / 1 | 3.5 | Yes |
| 11279 |  CHEMBL293381 | C24H30N4O | 390.531 | 3 / 1 | 4.4 | Yes |
| 12183 |  CHEMBL94880 | C18H25ClN4O | 348.875 | 3 / 2 | 3.4 | Yes |
| 12426 |  CHEMBL61825 | C22H33N5O2 | 399.539 | 4 / 2 | 2.8 | Yes |
| 12470 |  BDBM50359428 | C19H26N2O3S | 362.488 | 5 / 2 | 3.4 | Yes |
| 555536 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 15054 |  5-HT4 antagonist 1 | C23H36N4O5S | 480.624 | 8 / 1 | 1.2 | Yes |
| 17267 |  CHEMBL2440468 | C19H27N5O5S | 437.515 | 9 / 2 | 1.7 | Yes |
| 19241 |  CHEMBL156499 | C16H24ClN3O2 | 325.837 | 4 / 1 | 2.2 | Yes |
| 21455 |  BDBM50359429 | C18H24N2O3S | 348.461 | 5 / 2 | 3.1 | Yes |
| 21819 |  CHEMBL283483 | C19H18ClN3O2 | 355.822 | 4 / 1 | 2.7 | Yes |
| 21820 |  CHEMBL28499 | C19H18ClN3O2 | 355.822 | 4 / 1 | 2.7 | Yes |
| 25558 |  CHEMBL294484 | C25H31N5O2 | 433.556 | 4 / 2 | 3.4 | Yes |
| 26176 |  CHEMBL61308 | C17H24N4O | 300.406 | 3 / 1 | 2.4 | Yes |
| 26204 |  RS 39604 | C26H36ClN3O6S | 554.099 | 9 / 2 | 3.1 | No |
| 29315 |  CHEMBL303877 | C18H22ClN3O3 | 363.842 | 4 / 2 | 1.7 | Yes |
| 29546 |  CHEMBL158147 | C18H25ClN2O3 | 352.859 | 5 / 1 | 3.2 | Yes |
| 30035 |  Histaprodifen | C20H23N3 | 305.425 | 2 / 2 | 3.5 | Yes |
| 30303 |  BRL-25594 | C22H26ClN3O2 | 399.919 | 4 / 2 | 3.8 | Yes |
| 31089 |  BDBM50359427 | C21H30N2O3S | 390.542 | 5 / 2 | 4.5 | Yes |
| 32952 |  CHEMBL50660 | C17H25ClN2O3 | 340.848 | 5 / 1 | 3.4 | Yes |
| 32953 |  CHEMBL155917 | C17H25ClN2O3 | 340.848 | 5 / 1 | 3.4 | Yes |
| 33961 |  Clebopride | C20H24ClN3O2 | 373.881 | 4 / 2 | 3.2 | Yes |
| 34582 |  CHEMBL58803 | C23H28N4O | 376.504 | 3 / 1 | 4.0 | Yes |
| 34901 |  CHEMBL312898 | C16H21N3O2 | 287.363 | 4 / 2 | 1.1 | Yes |
| 34902 |  CHEMBL88263 | C16H21N3O2 | 287.363 | 4 / 2 | 1.1 | Yes |
| 36039 |  CHEMBL293790 | C20H30N4O | 342.487 | 3 / 1 | 3.5 | Yes |
| 36977 |  CHEMBL2431048 | C19H28ClN3O4 | 397.9 | 5 / 2 | N/A | N/A |
| 37559 |  CHEMBL291518 | C25H31FN4O3 | 454.546 | 5 / 1 | 4.1 | Yes |
| 555621 |  3-[2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one | C20H21F3N4O | 390.41 | 6 / 1 | 3.3 | Yes |
| 40093 |  CHEMBL116913 | C16H22ClN3O3 | 339.82 | 5 / 2 | 1.3 | Yes |
| 42756 |  BDBM50359426 | C22H27N3O2 | 365.477 | 3 / 2 | 3.3 | Yes |
| 48302 |  CHEMBL156088 | C17H24ClN2O3+ | 339.84 | 4 / 1 | 2.6 | Yes |
| 49493 |  CHEMBL291957 | C19H26N4O | 326.444 | 3 / 1 | 3.1 | Yes |
| 50572 |  UNII-87UKL3XE5X | C22H26N4O2 | 378.476 | 4 / 0 | 2.6 | Yes |
| 50580 |  CHEMBL285066 | C22H26N4O2 | 378.476 | 4 / 0 | 2.6 | Yes |
| 50712 |  CHEMBL150155 | C16H20N4O | 284.363 | 3 / 2 | 2.0 | Yes |
| 52821 |  BDBM50359434 | C20H25N3O3 | 355.438 | 4 / 2 | 1.8 | Yes |
| 53004 |  CHEMBL371883 | C19H25N3O2 | 327.428 | 3 / 1 | 3.0 | Yes |
| 53255 |  CHEMBL314299 | C25H31ClN4O | 439.0 | 3 / 1 | 5.1 | No |
| 53919 |  CHEMBL293918 | C24H29N5O2 | 419.529 | 4 / 1 | 2.9 | Yes |
| 523185 |  cisapride | C23H29ClFN3O4 | 465.95 | 7 / 2 | 3.4 | Yes |
| 56686 |  cisapride | C23H29ClFN3O4 | 465.95 | 7 / 2 | 3.4 | Yes |
| 523193 |  CHEMBL3759348 | C23H35ClN4O4 | 467.007 | 6 / 2 | 2.0 | Yes |
| 57510 |  CID 56850927 | C21H31ClN2O3S | 427.0 | 5 / 2 | N/A | N/A |
| 57862 |  CHEMBL156348 | C17H24ClN3O4 | 369.846 | 6 / 2 | 1.6 | Yes |
| 59987 |  CHEMBL558226 | C16H21Cl2N3O2 | 358.263 | 4 / 3 | N/A | N/A |
| 60735 |  CHEMBL59599 | C26H34N6O2 | 462.598 | 4 / 3 | 3.1 | Yes |
| 60934 |  CHEMBL3221572 | C18H25ClN4S | 364.936 | 3 / 2 | 4.0 | Yes |
| 61685 |  CHEMBL159891 | C15H20ClN3O3 | 325.793 | 5 / 2 | 1.0 | Yes |
| 61701 |  CHEMBL201878 | C16H19N3O2 | 285.347 | 4 / 1 | 2.7 | Yes |
| 62369 |  CHEMBL48698 | C15H22ClN3O3 | 327.809 | 5 / 2 | 2.3 | Yes |
| 62455 |  CHEMBL38041 | C20H27N3O2 | 341.455 | 3 / 0 | 2.8 | Yes |
| 66748 |  CHEMBL407493 | C15H18ClN5O | 319.793 | 4 / 3 | 1.3 | Yes |
| 67270 |  CHEMBL314198 | C20H29BrClN3O2 | 458.825 | 4 / 2 | N/A | N/A |
| 67271 |  CHEMBL423504 | C20H29BrClN3O2 | 458.825 | 4 / 2 | N/A | N/A |
| 67473 |  CHEMBL1926745 | C21H29N3O3 | 371.481 | 4 / 1 | 2.0 | Yes |
| 67774 |  BDBM50359423 | C20H24N4O2 | 352.438 | 4 / 2 | 1.8 | Yes |
| 68662 |  CHEMBL159825 | C15H20ClN3O2 | 309.794 | 4 / 2 | 1.7 | Yes |
| 71661 |  CHEMBL82976 | C27H38ClN3O6S | 568.126 | 9 / 2 | 3.5 | No |
| 523640 |  CHEMBL3758945 | C22H33ClN4O4 | 452.98 | 6 / 2 | 1.5 | Yes |
| 72142 |  CHEMBL301680 | C25H31FN6O2 | 466.561 | 5 / 3 | 3.3 | Yes |
| 72309 |  CHEMBL161841 | C15H20ClN3O2S | 341.854 | 5 / 2 | 1.8 | Yes |
| 75015 |  SB207710 | C19H27IN2O4 | 474.339 | 6 / 1 | 3.5 | Yes |
| 76135 |  CHEMBL57695 | C26H33N5O3 | 463.582 | 5 / 2 | 3.7 | Yes |
| 76361 |  ondansetron | C18H19N3O | 293.37 | 2 / 0 | 2.3 | Yes |
| 76563 |  (S)-zacopride | C15H20ClN3O2 | 309.794 | 4 / 2 | 1.7 | Yes |
| 76571 |  Zacopride | C15H20ClN3O2 | 309.794 | 4 / 2 | 1.7 | Yes |
| 76582 |  (R)-zacopride | C15H20ClN3O2 | 309.794 | 4 / 2 | 1.7 | Yes |
| 77262 |  SDZ-205557 | C14H21ClN2O3 | 300.783 | 5 / 1 | 3.2 | Yes |
| 77858 |  CID 56850799 | C20H26ClN3O3 | 391.896 | 4 / 2 | N/A | N/A |
| 78491 |  CHEMBL2431041 | C21H27ClN4O3 | 418.922 | 5 / 2 | N/A | N/A |
| 79231 |  CHEMBL147827 | C16H18ClN3O2 | 319.789 | 4 / 1 | 3.2 | Yes |
| 81981 |  CHEMBL79913 | C18H27ClN2O2 | 338.876 | 4 / 1 | 3.4 | Yes |
| 523950 |  CHEMBL3759944 | C25H39ClN4O4 | 495.061 | 6 / 2 | 2.9 | Yes |
| 83382 |  CHEMBL300476 | C14H19ClN2O2 | 282.768 | 3 / 1 | 3.0 | Yes |
| 555785 |  Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
| 85081 |  CHEMBL201946 | C17H20N2O2 | 284.359 | 3 / 1 | 3.7 | Yes |
| 86715 |  CHEMBL419112 | C26H35ClN2O4 | 475.026 | 6 / 1 | 4.9 | Yes |
| 87099 |  CHEMBL2431040 | C23H30ClN3O4 | 447.96 | 5 / 2 | N/A | N/A |
| 88793 |  CHEMBL3126112 | C16H21ClN2O4 | 340.804 | 6 / 1 | 2.2 | Yes |
| 89993 |  CHEMBL34224 | C14H19ClN2O3 | 298.767 | 5 / 1 | 2.3 | Yes |
| 92050 |  SC-53116 | C16H22ClN3O2 | 323.821 | 4 / 2 | 2.1 | Yes |
| 92055 |  CHEMBL37333 | C16H22ClN3O2 | 323.821 | 4 / 2 | 2.1 | Yes |
| 92057 |  CHEMBL37544 | C16H22ClN3O2 | 323.821 | 4 / 2 | 2.1 | Yes |
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