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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB207710
Molecular formula	C19H27IN2O4
IUPAC name	(1-butylpiperidin-4-yl)methyl 5-amino-6-iodo-2,3-dihydro-1,4-benzodioxine-8-carboxylate
Molecular weight	474.339
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.5
Synonyms	SB-207710 AC1NSKLR (1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-dihydrobenzo-[b][1,4]dioxine-5-carboxylate CHEMBL114112 L008862 (1-butyl-4-piperidinyl)-methyl-8-amino-7-iodo-1,4-benzodioxan-5-carboxyl-ate BDBM50327858 148703-08-6 D0B5MU SB 207710 8-Amino-7-iodo-2,3-dihydro-benzo[1,4]dioxine-5-carboxylic acid 1-butyl-piperidin-4-ylmethyl ester SCHEMBL2939430 (1-butylpiperidin-4-yl)methyl 5-amino-6-iodo-2,3-dihydro-1,4-benzodioxine-8-carboxylate GTPL257 [ Show all ]
Inchi Key	FCKKCDRMGKXQDK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3
PubChem CID	5311423
ChEMBL	CHEMBL114112
IUPHAR	257
BindingDB	50327858
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
75015	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
75017	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
75018	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
553645	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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