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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL201878
Molecular formula	C16H19N3O2
IUPAC name	[(1R,8S)-2,3,5,6,7,8-hexahydro-1H-pyrrolizin-1-yl]methyl 1H-indazole-3-carboxylate
Molecular weight	285.347
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.7
Synonyms	BDBM50181841 (1S,7aR)-hexahydro-1H-pyrrolizin-1-ylmethyl 1H-indazole-3-carboxylate
Inchi Key	DJPQWKJCTULKTC-FZMZJTMJSA-N
Inchi ID	InChI=1S/C16H19N3O2/c20-16(15-12-4-1-2-5-13(12)17-18-15)21-10-11-7-9-19-8-3-6-14(11)19/h1-2,4-5,11,14H,3,6-10H2,(H,17,18)/t11-,14-/m0/s1
PubChem CID	11508052
ChEMBL	CHEMBL201878
IUPHAR	N/A
BindingDB	50181841
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
61701	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
61703	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
61700	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
61705	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
61702	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
61704	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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